Blood pressure response evoked by ventral root afferent fibres in the cat

Jin Chung, J. Kim, H. K. Shin

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Systemic arterial blood pressure changes in response to stimulation of the distal stump of the cut spinal ventral root were investigated in anaesthetized, vagotomized, and carotid sinus-denervated cats. Low intensity electrical stimulation (<20 T, where T is threshold intensity) of the ventral root caused a rise in blood pressure. This elevation was abolished by paralysing the muscles with gallamine. This pressor response has been reported previously, and it is likely to be evoked by afferents excited by the contracting muscle. High intensity electrical stimulation (500 T) of the ventral root caused a second and marked pressor response. This was not affected by muscular paralysis or by cutting the sciatic nerve, but it was abolished by cutting the dorsal root. Threshold intensity of the second component of the pressor response was within the same range as the intensity needed for activation of C fibres in the ventral root, ranging between 200 T and 300 T. This response was graded with increasing stimulus intensity, and it showed both spatial and temporal summation. From the above results, we conclude that non-myelinated fibres in feline spinal ventral root course distally to the dorsal root ganglion and then enter the spinal cord via the dorsal root. Activation of these fibres results in a marked elevation of the systemic arterial blood pressure as in other somato-sympathetic reflexes induced by peripheral C fibre activation.

Original languageEnglish (US)
Pages (from-to)255-265
Number of pages11
JournalJournal of Physiology
VolumeVOL. 370
StatePublished - 1986
Externally publishedYes

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Spinal Nerve Roots
Cats
Blood Pressure
Unmyelinated Nerve Fibers
Electric Stimulation
Arterial Pressure
Gallamine Triethiodide
Muscles
Carotid Sinus
Felidae
Spinal Ganglia
Sciatic Nerve
Paralysis
Reflex
Spinal Cord

ASJC Scopus subject areas

  • Physiology

Cite this

Blood pressure response evoked by ventral root afferent fibres in the cat. / Chung, Jin; Kim, J.; Shin, H. K.

In: Journal of Physiology, Vol. VOL. 370, 1986, p. 255-265.

Research output: Contribution to journalArticle

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