Bone Graft Substitute: Allograft and Xenograft

Naohiro Shibuya, Daniel C. Jupiter

Research output: Contribution to journalReview articlepeer-review

118 Scopus citations


Rapid bone graft incorporation for structural rigidity is essential. Early range of motion, exercise, and weight-bearing are keys to rehabilitation. Structural and nonstructural bone grafts add length, height, and volume to alter alignment, function, and appearance. Bone graft types include: corticocancellous autograft, allograft, xenograft, and synthetic graft. Autogenic grafts are harvested from the patient, less likely to be rejected, and more likely to be incorporated; however, harvesting adds a procedure and donor site complication is common. Allografts, xenografts, and synthetic grafts eliminate secondary procedures and donor site complications; however, rejection and slower incorporation can occur.

Original languageEnglish (US)
Pages (from-to)21-34
Number of pages14
JournalClinics in Podiatric Medicine and Surgery
Issue number1
StatePublished - 2015


  • Ankle
  • Autogenous graft
  • Bone
  • Foot
  • Incorporation
  • Union

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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