@article{bc865b797b44435b9c234005338336a7,
title = "Bone tissue engineering techniques, advances, and scaffolds for treatment of bone defects",
abstract = "Bone tissue engineering (BTE) aims to develop strategies to regenerate damaged or diseased bone using a combination of cells, growth factors, and biomaterials. This article highlights recent advances in BTE, with particular emphasis on the role of the biomaterials as scaffolding material to heal bone defects. Studies encompass the utilization of bioceramics, composites, and myriad hydrogels that have been fashioned by injection molding, electrospinning, and 3D bioprinting over recent years, with the aim to provide an insight into the progress of BTE along with a commentary on their scope and possibilities to aid future research. The biocompatibility and structural efficacy of some of these biomaterials are also discussed.",
keywords = "3D printing, Bone defect, Electrospinning, Injection molding, Orthopedics, Tissue engineering",
author = "Matthew Alonzo and {Alvarez Primo}, Fabian and {Anil Kumar}, Shweta and Mudloff, {Joel A.} and Erick Dominguez and Gisel Fregoso and Nick Ortiz and Weiss, {William M.} and Binata Joddar",
note = "Funding Information: The Joddar Lab (IMSTEL) acknowledges the NSF ( CBET 1927628 ). Matthew Alonzo acknowledges the Eloise E. and Patrick B. Wieland fellowship at UTEP and the Gates Millennium Scholarship Program. Authors also acknowledge support for materials and supplies for the study summarized in Figure 4 (bottom panel) obtained from the NSF-MRI ( DMR 1826268 ). The authors also acknowledge the GF acknowledges the National Institute of General Medical Sciences of the National Institutes of Health under RL5GM118969 , TL4GM118971 , and UL1GM118970 . Funding Information: The Joddar Lab (IMSTEL) acknowledges the NSF (CBET 1927628). Matthew Alonzo acknowledges the Eloise E. and Patrick B. Wieland fellowship at UTEP and the Gates Millennium Scholarship Program. Authors also acknowledge support for materials and supplies for the study summarized in Figure 4 (bottom panel) obtained from the NSF-MRI (DMR 1826268). The authors also acknowledge the GF acknowledges the National Institute of General Medical Sciences of the National Institutes of Health under RL5GM118969, TL4GM118971, and UL1GM118970. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",
year = "2021",
month = mar,
doi = "10.1016/j.cobme.2020.100248",
language = "English (US)",
volume = "17",
journal = "Current Opinion in Biomedical Engineering",
issn = "2468-4511",
publisher = "Elsevier BV",
}