Brazilian spotted fever in Espirito Santo, Brazil

Description of a focus of infection in a new endemic region

D. J. Sexton, M. Muniz, G. R. Corey, E. B. Breitschwerdt, B. C. Hegarty, S. Dumler, David Walker, P. M. Pecanha, R. Dietze

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Although Brazilian spotted fever is known to occur in several adjacent states, infection with spotted fever group (SFG) rickettsiae has not previously been documented in the Brazilian state of Espirito Santo. We report a cluster of two proven and four suspected cases of Brazilian spotted fever in a small valley near Colatina, Espirito Santo. Four patients died without confirmatory serologic or pathologic studies. The two surviving patients had serologic and/or pathologic evidence of infection with SFG rickettsiae. Results of a survey done in 1991 confirmed the presence of antibodies reactive with SFG rickettsiae in the serum of dogs living in this region. Two of 25 dogs had elevated microimmunofluorescent antibody titers (1:64 and 1:256). Both seropositive dogs were pets of the index cases and lived in the valley where all six human cases were presumed to have acquired their infections. These cases and the results of the canine serosurvey suggest that a focus of virulent disease exists in an area not previously known to be endemic for SFG rickettsiae.

Original languageEnglish (US)
Pages (from-to)222-226
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume49
Issue number2
StatePublished - 1993
Externally publishedYes

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Brazil
Rickettsia
Fever
Infection
Dogs
Antibodies
Pets
Canidae
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Sexton, D. J., Muniz, M., Corey, G. R., Breitschwerdt, E. B., Hegarty, B. C., Dumler, S., ... Dietze, R. (1993). Brazilian spotted fever in Espirito Santo, Brazil: Description of a focus of infection in a new endemic region. American Journal of Tropical Medicine and Hygiene, 49(2), 222-226.

Brazilian spotted fever in Espirito Santo, Brazil : Description of a focus of infection in a new endemic region. / Sexton, D. J.; Muniz, M.; Corey, G. R.; Breitschwerdt, E. B.; Hegarty, B. C.; Dumler, S.; Walker, David; Pecanha, P. M.; Dietze, R.

In: American Journal of Tropical Medicine and Hygiene, Vol. 49, No. 2, 1993, p. 222-226.

Research output: Contribution to journalArticle

Sexton, DJ, Muniz, M, Corey, GR, Breitschwerdt, EB, Hegarty, BC, Dumler, S, Walker, D, Pecanha, PM & Dietze, R 1993, 'Brazilian spotted fever in Espirito Santo, Brazil: Description of a focus of infection in a new endemic region', American Journal of Tropical Medicine and Hygiene, vol. 49, no. 2, pp. 222-226.
Sexton, D. J. ; Muniz, M. ; Corey, G. R. ; Breitschwerdt, E. B. ; Hegarty, B. C. ; Dumler, S. ; Walker, David ; Pecanha, P. M. ; Dietze, R. / Brazilian spotted fever in Espirito Santo, Brazil : Description of a focus of infection in a new endemic region. In: American Journal of Tropical Medicine and Hygiene. 1993 ; Vol. 49, No. 2. pp. 222-226.
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