Bronchopulmonary dysplasia: its effects upon the heart and lungs.

M. T. Verklan

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Bronchopulmonary dysplasia (BPD) is one of the most significant sequelae of prematurity, affecting the pulmonary and cardiovascular structures especially. From the first weeks of life, there exists a close anatomical and functional relationship between these two systems. Changes in intrathoracic pressure or pulmonary vascular resistance greatly impact both the left and right sides of the heart. In turn, increasing afterload and decreasing preload affect blood flow through the lung, as well as the state of oxygenation and ventilation. BPD affects the function, growth, and development of the heart and lung, due to the hypoxia, acidosis, hyperoxia, and fibrosis associated with the fibroproliferative repair process. Significance of clinical findings and the role of the bedside caregiver are also discussed.

Original languageEnglish (US)
Pages (from-to)5-12
Number of pages8
JournalNeonatal network : NN
Volume16
Issue number8
StatePublished - 1997
Externally publishedYes

Fingerprint

Bronchopulmonary Dysplasia
Lung
Hyperoxia
Acidosis
Growth and Development
Vascular Resistance
Caregivers
Ventilation
Fibrosis
Pressure

Cite this

Bronchopulmonary dysplasia : its effects upon the heart and lungs. / Verklan, M. T.

In: Neonatal network : NN, Vol. 16, No. 8, 1997, p. 5-12.

Research output: Contribution to journalArticle

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