Bussuquara Virus: A Neglected Orthoflavivirus with Broad Distribution Across Central and South America and the Caribbean

Madeline R. Steck; Michaela Buenemann; Nikos Vasilakis

doi:10.3390/v17020183

Bussuquara Virus: A Neglected Orthoflavivirus with Broad Distribution Across Central and South America and the Caribbean

Madeline R. Steck, Michaela Buenemann, Nikos Vasilakis

Pathology

Research output: Contribution to journal › Review article › peer-review

Abstract

Bussuquara virus (BSQV) was first discovered in the Brazilian Amazon in 1956. It is an arthropod-borne virus (arbovirus) in the genus Orthoflavivirus, family Flaviviridae. Since its discovery, BSQV has been sporadically detected across the South (Brazil, Columbia, and Argentina) and Central (Panama and Mexico) America and the Caribbean (Grenada), but there is minimal BSQV surveillance due to limited public health awareness and a lack of specific or sensitive diagnostics. BSQV exposure has been reported in a wide range of host and vector species, including humans. Little information is available in the literature and herein we summarize the published historical findings on BSQV and suggest a pathway for future studies to better understand its potential emergence into human populations.

Original language	English (US)
Article number	183
Journal	Viruses
Volume	17
Issue number	2
DOIs	https://doi.org/10.3390/v17020183
State	Published - Feb 2025

Keywords

clinical manifestations
mosquito-borne virus
orthoflavivirus
transmission cycles

ASJC Scopus subject areas

Infectious Diseases
Virology

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10.3390/v17020183

Cite this

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title = "Bussuquara Virus: A Neglected Orthoflavivirus with Broad Distribution Across Central and South America and the Caribbean",

abstract = "Bussuquara virus (BSQV) was first discovered in the Brazilian Amazon in 1956. It is an arthropod-borne virus (arbovirus) in the genus Orthoflavivirus, family Flaviviridae. Since its discovery, BSQV has been sporadically detected across the South (Brazil, Columbia, and Argentina) and Central (Panama and Mexico) America and the Caribbean (Grenada), but there is minimal BSQV surveillance due to limited public health awareness and a lack of specific or sensitive diagnostics. BSQV exposure has been reported in a wide range of host and vector species, including humans. Little information is available in the literature and herein we summarize the published historical findings on BSQV and suggest a pathway for future studies to better understand its potential emergence into human populations.",

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KW - transmission cycles

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Bussuquara Virus: A Neglected Orthoflavivirus with Broad Distribution Across Central and South America and the Caribbean

Abstract

Keywords

ASJC Scopus subject areas

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