Cadaveric allograft discards as a result of positive skin cultures

M. K. Obeng, R. L. McCauley, J. R. Barnett, J. P. Heggers, K. Sheridan, S. S. Schutzler

    Research output: Contribution to journalArticle

    22 Citations (Scopus)

    Abstract

    Introduction: the availability of cadaveric allograft is often limited by potentially pathogenic microbial organisms. Little data exists on cadaveric allograft discard rates related to positive microbiology. The purpose of this retrospective review was to determine the cadaveric allograft discard rates related positive microbiology and the subsequent breakdown of those organisms involved. Methods: from January 1995 to June 1997, 1112 donors were screened and procured after informed consent had been obtained. The procedures used were in accordance with American Association of Tissue Banks (AATB) standards and guidelines. The number of discards due to positive skin cultures was reviewed and analyzed for type of microbial organism. Results: fifty-four donors (4.9%) were discarded due to positive skin cultures. Methicillin resistant Staphylococcus epidermidis, (MRSE), was the most predominant organism (22.2%), followed by gram negative rods as a group (18.5%), with Aspergillus species being the least predominant isolate. Conclusion: despite the strict adherence to AATB protocol, microbial contamination of cadaveric allograft skin does not reach zero. It is not surprising that S. epidermidis was the predominant isolate, since skin is one of its common habitats. Continued vigilance in microbial testing remains paramount to ensure the quality of the allograft.

    Original languageEnglish (US)
    Pages (from-to)267-271
    Number of pages5
    JournalBurns
    Volume27
    Issue number3
    DOIs
    StatePublished - 2001

    Fingerprint

    Allografts
    Skin
    Tissue Banks
    Staphylococcus epidermidis
    Microbiology
    Methicillin Resistance
    Aspergillus
    Informed Consent
    Ecosystem
    Guidelines

    Keywords

    • Cadaveric allograft
    • MRSE
    • Staphylococcus epidermidis

    ASJC Scopus subject areas

    • Emergency Medicine
    • Surgery

    Cite this

    Obeng, M. K., McCauley, R. L., Barnett, J. R., Heggers, J. P., Sheridan, K., & Schutzler, S. S. (2001). Cadaveric allograft discards as a result of positive skin cultures. Burns, 27(3), 267-271. https://doi.org/10.1016/S0305-4179(00)00116-9

    Cadaveric allograft discards as a result of positive skin cultures. / Obeng, M. K.; McCauley, R. L.; Barnett, J. R.; Heggers, J. P.; Sheridan, K.; Schutzler, S. S.

    In: Burns, Vol. 27, No. 3, 2001, p. 267-271.

    Research output: Contribution to journalArticle

    Obeng, MK, McCauley, RL, Barnett, JR, Heggers, JP, Sheridan, K & Schutzler, SS 2001, 'Cadaveric allograft discards as a result of positive skin cultures', Burns, vol. 27, no. 3, pp. 267-271. https://doi.org/10.1016/S0305-4179(00)00116-9
    Obeng MK, McCauley RL, Barnett JR, Heggers JP, Sheridan K, Schutzler SS. Cadaveric allograft discards as a result of positive skin cultures. Burns. 2001;27(3):267-271. https://doi.org/10.1016/S0305-4179(00)00116-9
    Obeng, M. K. ; McCauley, R. L. ; Barnett, J. R. ; Heggers, J. P. ; Sheridan, K. ; Schutzler, S. S. / Cadaveric allograft discards as a result of positive skin cultures. In: Burns. 2001 ; Vol. 27, No. 3. pp. 267-271.
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