Abstract
Salmonella typhimurium cultured with physiological levels of calcium are significantly enhanced in their ability to penetrate HeLa cells in vitro. Increased infectivity was not observed in magnesium-supplemented media, but was demonstrated in calcium-supplemented minimal defined or calcium-supplemented cation-deficient media. Invasion enhancement was observed for a number of S. typhimurium strains and ranged from 28-390% over calcium-deficient controls. Enhanced HeLa cell infectivity was not dependent on the presence of an autonomous 60-MDa plasmid.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 299-304 |
| Number of pages | 6 |
| Journal | FEMS Microbiology Letters |
| Volume | 41 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1987 |
Keywords
- Calcium
- HeLa cell invasion
- Salmonella typhimurium
- Virulence
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
- Genetics
Fingerprint
Dive into the research topics of 'Calcium enhances Salmonella typhimurium invasion of HeLa cells'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS