Canine gallbladder cyclic motor activity

T. Matsumoto, S. K. Sarna, R. E. Condon, W. J. Dodds, N. Mochinaga

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We investigated whether the gallbladder has cyclic motor activity similar to that of the stomach, lower esophageal sphincter, and sphincter of Oddi in the fasted state. We found that the canine gallbladder infundibulum exhibited a cyclic burst of short duration (69 ± 3 s) contractions that were closely associated with phase III activity of the antrum. The cyclic motor activity was sometimes less prominent or absent in the body and the fundus of the gallbladder. The mean period of gallbladder cyclic motor activity was not significantly different from the mean period of phase III activity in the stomach and the duodenum. The cyclic bursts of gallbladder contractions lasted for 21 ± 2 min. The gallbladder cyclic motor activity started at about the same time as the antral phase III activity, and both of these activities started ~12 min earlier than the duodenal phase III activity. In addition to the aforementioned cyclic bursts of contractions, the gallbladder sometimes exhibited long duration (6.4 ± 0.6 min) contractions that occurred irregularly and unpredictably during the duodenal migrating motor complex cycle. We conclude that during fasting the canine gallbladder has a cyclic motor activity that is temporally related to phase III activity of the stomach and the duodenum. The role of short duration phasic contractions during cyclic motor activity may be to periodically stir gallbladder contents, whereas the long duration contractions may partially empty the gallbladder in the fasted state.

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Gastrointestinal and Liver Physiology
Volume255
Issue number4
StatePublished - 1988
Externally publishedYes

Fingerprint

Gallbladder
Canidae
Motor Activity
Stomach
Duodenum
Migrating Myoelectric Complexes
Sphincter of Oddi
Lower Esophageal Sphincter
Pituitary Gland
Fasting

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

Cite this

Matsumoto, T., Sarna, S. K., Condon, R. E., Dodds, W. J., & Mochinaga, N. (1988). Canine gallbladder cyclic motor activity. American Journal of Physiology - Gastrointestinal and Liver Physiology, 255(4).

Canine gallbladder cyclic motor activity. / Matsumoto, T.; Sarna, S. K.; Condon, R. E.; Dodds, W. J.; Mochinaga, N.

In: American Journal of Physiology - Gastrointestinal and Liver Physiology, Vol. 255, No. 4, 1988.

Research output: Contribution to journalArticle

Matsumoto, T, Sarna, SK, Condon, RE, Dodds, WJ & Mochinaga, N 1988, 'Canine gallbladder cyclic motor activity', American Journal of Physiology - Gastrointestinal and Liver Physiology, vol. 255, no. 4.
Matsumoto, T. ; Sarna, S. K. ; Condon, R. E. ; Dodds, W. J. ; Mochinaga, N. / Canine gallbladder cyclic motor activity. In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 1988 ; Vol. 255, No. 4.
@article{feb66bffbb38462f8e97df4179c41352,
title = "Canine gallbladder cyclic motor activity",
abstract = "We investigated whether the gallbladder has cyclic motor activity similar to that of the stomach, lower esophageal sphincter, and sphincter of Oddi in the fasted state. We found that the canine gallbladder infundibulum exhibited a cyclic burst of short duration (69 ± 3 s) contractions that were closely associated with phase III activity of the antrum. The cyclic motor activity was sometimes less prominent or absent in the body and the fundus of the gallbladder. The mean period of gallbladder cyclic motor activity was not significantly different from the mean period of phase III activity in the stomach and the duodenum. The cyclic bursts of gallbladder contractions lasted for 21 ± 2 min. The gallbladder cyclic motor activity started at about the same time as the antral phase III activity, and both of these activities started ~12 min earlier than the duodenal phase III activity. In addition to the aforementioned cyclic bursts of contractions, the gallbladder sometimes exhibited long duration (6.4 ± 0.6 min) contractions that occurred irregularly and unpredictably during the duodenal migrating motor complex cycle. We conclude that during fasting the canine gallbladder has a cyclic motor activity that is temporally related to phase III activity of the stomach and the duodenum. The role of short duration phasic contractions during cyclic motor activity may be to periodically stir gallbladder contents, whereas the long duration contractions may partially empty the gallbladder in the fasted state.",
author = "T. Matsumoto and Sarna, {S. K.} and Condon, {R. E.} and Dodds, {W. J.} and N. Mochinaga",
year = "1988",
language = "English (US)",
volume = "255",
journal = "American Journal of Physiology - Endocrinology and Metabolism",
issn = "0193-1849",
publisher = "American Physiological Society",
number = "4",

}

TY - JOUR

T1 - Canine gallbladder cyclic motor activity

AU - Matsumoto, T.

AU - Sarna, S. K.

AU - Condon, R. E.

AU - Dodds, W. J.

AU - Mochinaga, N.

PY - 1988

Y1 - 1988

N2 - We investigated whether the gallbladder has cyclic motor activity similar to that of the stomach, lower esophageal sphincter, and sphincter of Oddi in the fasted state. We found that the canine gallbladder infundibulum exhibited a cyclic burst of short duration (69 ± 3 s) contractions that were closely associated with phase III activity of the antrum. The cyclic motor activity was sometimes less prominent or absent in the body and the fundus of the gallbladder. The mean period of gallbladder cyclic motor activity was not significantly different from the mean period of phase III activity in the stomach and the duodenum. The cyclic bursts of gallbladder contractions lasted for 21 ± 2 min. The gallbladder cyclic motor activity started at about the same time as the antral phase III activity, and both of these activities started ~12 min earlier than the duodenal phase III activity. In addition to the aforementioned cyclic bursts of contractions, the gallbladder sometimes exhibited long duration (6.4 ± 0.6 min) contractions that occurred irregularly and unpredictably during the duodenal migrating motor complex cycle. We conclude that during fasting the canine gallbladder has a cyclic motor activity that is temporally related to phase III activity of the stomach and the duodenum. The role of short duration phasic contractions during cyclic motor activity may be to periodically stir gallbladder contents, whereas the long duration contractions may partially empty the gallbladder in the fasted state.

AB - We investigated whether the gallbladder has cyclic motor activity similar to that of the stomach, lower esophageal sphincter, and sphincter of Oddi in the fasted state. We found that the canine gallbladder infundibulum exhibited a cyclic burst of short duration (69 ± 3 s) contractions that were closely associated with phase III activity of the antrum. The cyclic motor activity was sometimes less prominent or absent in the body and the fundus of the gallbladder. The mean period of gallbladder cyclic motor activity was not significantly different from the mean period of phase III activity in the stomach and the duodenum. The cyclic bursts of gallbladder contractions lasted for 21 ± 2 min. The gallbladder cyclic motor activity started at about the same time as the antral phase III activity, and both of these activities started ~12 min earlier than the duodenal phase III activity. In addition to the aforementioned cyclic bursts of contractions, the gallbladder sometimes exhibited long duration (6.4 ± 0.6 min) contractions that occurred irregularly and unpredictably during the duodenal migrating motor complex cycle. We conclude that during fasting the canine gallbladder has a cyclic motor activity that is temporally related to phase III activity of the stomach and the duodenum. The role of short duration phasic contractions during cyclic motor activity may be to periodically stir gallbladder contents, whereas the long duration contractions may partially empty the gallbladder in the fasted state.

UR - http://www.scopus.com/inward/record.url?scp=0023753115&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023753115&partnerID=8YFLogxK

M3 - Article

C2 - 3177641

AN - SCOPUS:0023753115

VL - 255

JO - American Journal of Physiology - Endocrinology and Metabolism

JF - American Journal of Physiology - Endocrinology and Metabolism

SN - 0193-1849

IS - 4

ER -