Carcinoid Heart Disease: A Guide for Clinicians

Daniel Perry, Salim S. Hayek

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Carcinoid heart disease is the collective term for all cardiac manifestations that develop in patients with carcinoid. The cardiac manifestations of carcinoid tumors are attributed to the paraneoplastic effects of vasoactive substances released by the malignant cells. The clinical manifestations of carcinoid heart disease include valvular destruction leading to valvular regurgitation and stenosis, right-sided heart failure, and metastatic carcinoid disease. A combination of biomarkers and cardiac imaging is used in screening and diagnosis of carcinoid heart disease in patients with carcinoid syndrome. The management of carcinoid heart disease involves medical and surgical treatment and requires a multidisciplinary approach for optimized care.

Original languageEnglish (US)
Pages (from-to)497-503
Number of pages7
JournalCardiology Clinics
Issue number4
StatePublished - Nov 2019
Externally publishedYes


  • Carcinoid syndrome
  • HIAA
  • Pulmonic valve
  • Regurgitation
  • Right heart failure
  • Tricuspid valve

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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