TY - JOUR
T1 - Cardiopulmonary reference standards in the pregnant sheep (Ovis aries)
T2 - A comparative study of ovine and human physiology in obstetrics
AU - Cissik, John H.
AU - Ehler, William J.
AU - Hankins, Gary D.
AU - Snyder, Rüssel R.
PY - 1991
Y1 - 1991
N2 - 1. 1. Complete blood counts, respiratory rate, tidal volume, arterial and mixed venous blood gases; heart rate, cardiac output, and arterial, pulmonary artery, central venous and pulmonary wedge pressures were determined in 10 pregnant adult sheep of 42.7-65.7 kg body weight. 2. 2. Arithmetic means, standard deviations, and coefficients of variation were calculated to develop reference values; in addition, the 95% confidence limits for ranges were established. 3. 3. Comparison of derived data with that from non-pregnant sheep shows changes similar to those seen when examining pregnant and non-pregnant humans. 4. 4. These results indicate the pregnant sheep is an acceptable model for human obstetrical research.
AB - 1. 1. Complete blood counts, respiratory rate, tidal volume, arterial and mixed venous blood gases; heart rate, cardiac output, and arterial, pulmonary artery, central venous and pulmonary wedge pressures were determined in 10 pregnant adult sheep of 42.7-65.7 kg body weight. 2. 2. Arithmetic means, standard deviations, and coefficients of variation were calculated to develop reference values; in addition, the 95% confidence limits for ranges were established. 3. 3. Comparison of derived data with that from non-pregnant sheep shows changes similar to those seen when examining pregnant and non-pregnant humans. 4. 4. These results indicate the pregnant sheep is an acceptable model for human obstetrical research.
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U2 - 10.1016/0300-9629(91)90307-X
DO - 10.1016/0300-9629(91)90307-X
M3 - Article
C2 - 1685379
AN - SCOPUS:0025948845
SN - 1095-6433
VL - 100
SP - 877
EP - 880
JO - Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
JF - Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
IS - 4
ER -