TY - JOUR
T1 - Caring for critically ill patients with Ebola virus disease
T2 - Perspectives from West Africa
AU - Fowler, Robert A.
AU - Fletcher, Thomas
AU - Fischer, William A.
AU - Lamontagne, Francois
AU - Jacob, Shevin
AU - Brett-Major, David
AU - Lawler, James V.
AU - Jacquerioz, Frederique A.
AU - Houlihan, Catherine
AU - O'Dempsey, Tim
AU - Ferri, Mauricio
AU - Adachi, Takuya
AU - Lamah, Marie Claire
AU - Bah, Elhadj Ibrahima
AU - Mayet, Thierry
AU - Schieffelin, John
AU - McLellan, Susan L.
AU - Senga, Mikiko
AU - Kato, Yasuyuki
AU - Clement, Christophe
AU - Mardel, Simon
AU - De Villar, Rosa Constanza Vallenas Bejar
AU - Shindo, Nahoko
AU - Bausch, Daniel
N1 - Publisher Copyright:
Copyright © 2014 by the American Thoracic Society.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - The largest ever Ebola virus disease outbreak is ravaging West Africa. The constellation of little public health infrastructure, low levels of health literacy, limited acute care and infection prevention and control resources, densely populated areas, and a highly transmissible and lethal viral infection have led to thousands of confirmed, probable, or suspected cases thus far. Ebola virus disease is characterized by a febrile severe illness with profound gastrointestinal manifestations and is complicated by intravascular volume depletion, shock, profound electrolyte abnormalities, and organ dysfunction. Despite no proven Ebola virus-specific medical therapies, the potential effect of supportive care is great for a condition with high baseline mortality and one usually occurring in resource-constrained settings.Withmore personnel, basic monitoring, and supportive treatment, many of the sickest patientswith Ebola virus disease do not need to die. Ebola virus disease represents an illness ready for a paradigmshift in care delivery and outcomes, and the profession of critical care medicine can and should be instrumental in helping this happen.
AB - The largest ever Ebola virus disease outbreak is ravaging West Africa. The constellation of little public health infrastructure, low levels of health literacy, limited acute care and infection prevention and control resources, densely populated areas, and a highly transmissible and lethal viral infection have led to thousands of confirmed, probable, or suspected cases thus far. Ebola virus disease is characterized by a febrile severe illness with profound gastrointestinal manifestations and is complicated by intravascular volume depletion, shock, profound electrolyte abnormalities, and organ dysfunction. Despite no proven Ebola virus-specific medical therapies, the potential effect of supportive care is great for a condition with high baseline mortality and one usually occurring in resource-constrained settings.Withmore personnel, basic monitoring, and supportive treatment, many of the sickest patientswith Ebola virus disease do not need to die. Ebola virus disease represents an illness ready for a paradigmshift in care delivery and outcomes, and the profession of critical care medicine can and should be instrumental in helping this happen.
KW - Africa
KW - Critical care
KW - Ebola
KW - Outbreak
KW - Viral hemorrhagic fever
UR - http://www.scopus.com/inward/record.url?scp=84914136258&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84914136258&partnerID=8YFLogxK
U2 - 10.1164/rccm.201408-1514CP
DO - 10.1164/rccm.201408-1514CP
M3 - Article
C2 - 25166884
AN - SCOPUS:84914136258
SN - 1073-449X
VL - 190
SP - 733
EP - 737
JO - American Journal of Respiratory and Critical Care Medicine
JF - American Journal of Respiratory and Critical Care Medicine
IS - 7
ER -