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Carotenoid Intake and Supplementation in Cancer: Pro and Con

  • Werner G. Siems
  • , Olaf Sommerburg
  • , Ingrid Wiswedel
  • , Peter M. Eckl
  • , Nikolaus Bresgen
  • , Frederik J.G.M. van Kuijk
  • , Carlo Crifò
  • , Costantino Salerno

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The aim of this review is to summarize the literature data concerning statistical correlations between carotenoid intake and cancer and to provide evidence, if any, that can justify carotenoid supplementation in protocols designed for the prevention and the treatment of cancer diseases. Particular attention will be drawn to lung cancer because of its surprisingly high incidence in cigarette smokers and asbestos workers who received high doses of β-carotene. The efcacy of carotenoids and retinol as adjuvants in the therapeutic procedures against cancer and the clinical indications for carotenoid supplementation will be discussed.

Original languageEnglish (US)
Title of host publicationCarotenoids and Vitamin A in Translational Medicine
PublisherCRC Press
Pages225-258
Number of pages34
ISBN (Electronic)9781439855270
ISBN (Print)9781439855263
DOIs
StatePublished - Jan 1 2013
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine
  • General Agricultural and Biological Sciences
  • General Chemistry
  • General Biochemistry, Genetics and Molecular Biology

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