Case report

Guillain-barré syndrome after zika virus infection in Brazil

Mateus Santana Do Rosário, Pedro Antonio Pereira De Jesus, Nikos Vasilakis, Daniel Santana Farias, Marco Antônio Caires Novaes, Sueli Guerreiro Rodrigues, Lívia Caricio Martins, Pedro Fernando Da Costa Vasconcelos, Albert Icksang Ko, Luiz Carlos Junior Alcântara, Isadora Cristina De Siqueira

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

Zika virus (ZIKV) is an emerging flavivirus, which has caused a widespread outbreak in the Americas. Shortly after its introduction in 2015, a cluster of cases with Guillain-Barré syndrome was detected in Brazil. Herein, we describe two cases from the city of Salvador, who developed ascending paresis after an acute exanthematous illness. The patients were admitted to the intensive care unit with tetraparesis and cranial nerve palsy, which resolved after intravenous administration of human immunoglobulin. Serological evaluation detected IgM-specific ZIKV antibodies. In regions of Zika virus transmission, health-care workers must be aware of the potential severe neurological complications associated with ZIKV infection and be prepared to provide prompt diagnosis, treatment, and supportive care.

Original languageEnglish (US)
Pages (from-to)1157-1160
Number of pages4
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume95
Issue number5
DOIs
StatePublished - Nov 1 2016

Fingerprint

Brazil
Cranial Nerve Diseases
Flavivirus
Paresis
Intravenous Administration
Disease Outbreaks
Immunoglobulin M
Intensive Care Units
Immunoglobulins
Delivery of Health Care
Antibodies
Zika Virus Infection
Zika Virus
Therapeutics

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Do Rosário, M. S., De Jesus, P. A. P., Vasilakis, N., Farias, D. S., Novaes, M. A. C., Rodrigues, S. G., ... De Siqueira, I. C. (2016). Case report: Guillain-barré syndrome after zika virus infection in Brazil. American Journal of Tropical Medicine and Hygiene, 95(5), 1157-1160. https://doi.org/10.4269/ajtmh.16-0306

Case report : Guillain-barré syndrome after zika virus infection in Brazil. / Do Rosário, Mateus Santana; De Jesus, Pedro Antonio Pereira; Vasilakis, Nikos; Farias, Daniel Santana; Novaes, Marco Antônio Caires; Rodrigues, Sueli Guerreiro; Martins, Lívia Caricio; Da Costa Vasconcelos, Pedro Fernando; Ko, Albert Icksang; Alcântara, Luiz Carlos Junior; De Siqueira, Isadora Cristina.

In: American Journal of Tropical Medicine and Hygiene, Vol. 95, No. 5, 01.11.2016, p. 1157-1160.

Research output: Contribution to journalArticle

Do Rosário, MS, De Jesus, PAP, Vasilakis, N, Farias, DS, Novaes, MAC, Rodrigues, SG, Martins, LC, Da Costa Vasconcelos, PF, Ko, AI, Alcântara, LCJ & De Siqueira, IC 2016, 'Case report: Guillain-barré syndrome after zika virus infection in Brazil', American Journal of Tropical Medicine and Hygiene, vol. 95, no. 5, pp. 1157-1160. https://doi.org/10.4269/ajtmh.16-0306
Do Rosário, Mateus Santana ; De Jesus, Pedro Antonio Pereira ; Vasilakis, Nikos ; Farias, Daniel Santana ; Novaes, Marco Antônio Caires ; Rodrigues, Sueli Guerreiro ; Martins, Lívia Caricio ; Da Costa Vasconcelos, Pedro Fernando ; Ko, Albert Icksang ; Alcântara, Luiz Carlos Junior ; De Siqueira, Isadora Cristina. / Case report : Guillain-barré syndrome after zika virus infection in Brazil. In: American Journal of Tropical Medicine and Hygiene. 2016 ; Vol. 95, No. 5. pp. 1157-1160.
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