Cellular mechanotransduction

Filamin A strains to regulate motility

Christopher D. Lynch, Michael Sheetz

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Abstract

A new study suggests that mechanical strain through the actin-binding protein filamin A leads to increased linkage between the extracellular matrix and cytoskeleton and decreased actin dynamics.

Original languageEnglish (US)
JournalCurrent Biology
Volume21
Issue number22
DOIs
StatePublished - Nov 22 2011
Externally publishedYes

Fingerprint

microfilament proteins
Cellular Mechanotransduction
filamin
Filamins
Microfilament Proteins
cytoskeleton
Actin Cytoskeleton
extracellular matrix
actin
Extracellular Matrix
linkage (genetics)
Actins
mechanotransduction

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Cellular mechanotransduction : Filamin A strains to regulate motility. / Lynch, Christopher D.; Sheetz, Michael.

In: Current Biology, Vol. 21, No. 22, 22.11.2011.

Research output: Contribution to journalShort survey

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