Central connections of ventral root afferents as demonstrated by the HRP method

C. W. Maynard, R. B. Leonard, J. D. Coulter, R. E. Coggeshall

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

To study the central connections of ventral root afferents, horse radish peroxidase was injected into the lumbosacral spinal cord of the cat and the appropriate dorsal root ganglia were examined from segments with (1) both dorsal and ventral roots intact, (2) both roots sectioned, and (3) only the dorsal root sectioned. The key finding was that a number of labeled cells (up to 133) were observed in the ganglion after dorsal rhizotomy. We interpret these findings to mean that the central processes of the labeled cells projected to the spinal cord through the ventral root. As expected, when both roots were cut, almost no cells were labeled and when both roots were intact, there were large numbers of labeled cells. Of the labeled cells observed in ganglia after dorsal rhizotomy, all were found to be within the ganglion itself. No labeled aberrant dorsal root ganglion cells could be found.

Original languageEnglish (US)
Pages (from-to)601-608
Number of pages8
JournalJournal of Comparative Neurology
Volume172
Issue number4
StatePublished - 1977

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Spinal Nerve Roots
Ganglia
Rhizotomy
Spinal Ganglia
Spinal Cord
Cell Count
Raphanus
Peroxidase
Cats

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Maynard, C. W., Leonard, R. B., Coulter, J. D., & Coggeshall, R. E. (1977). Central connections of ventral root afferents as demonstrated by the HRP method. Journal of Comparative Neurology, 172(4), 601-608.

Central connections of ventral root afferents as demonstrated by the HRP method. / Maynard, C. W.; Leonard, R. B.; Coulter, J. D.; Coggeshall, R. E.

In: Journal of Comparative Neurology, Vol. 172, No. 4, 1977, p. 601-608.

Research output: Contribution to journalArticle

Maynard, CW, Leonard, RB, Coulter, JD & Coggeshall, RE 1977, 'Central connections of ventral root afferents as demonstrated by the HRP method', Journal of Comparative Neurology, vol. 172, no. 4, pp. 601-608.
Maynard CW, Leonard RB, Coulter JD, Coggeshall RE. Central connections of ventral root afferents as demonstrated by the HRP method. Journal of Comparative Neurology. 1977;172(4):601-608.
Maynard, C. W. ; Leonard, R. B. ; Coulter, J. D. ; Coggeshall, R. E. / Central connections of ventral root afferents as demonstrated by the HRP method. In: Journal of Comparative Neurology. 1977 ; Vol. 172, No. 4. pp. 601-608.
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