Central hemodynamic assessment of normal term pregnancy

Steven L. Clark, David B. Cotton, Wesley Lee, Clark Bishop, Tracy Hill, James Southwick, James Pivarnik, Thomas Spillman, Greggory R. DeVore, Jeffrey Phelan, Gary Hankins, Thomas J. Benedetti, Dennis Tolley

Research output: Contribution to journalArticle

369 Citations (Scopus)

Abstract

Ten carefully screened primiparous patients between 36 and 38 weeks' gestation underwent pulmonary artery catheterization, arterial line placement, and central hemodynamic assessment in the left lateral recumbent position. Studies were repeated in the same patients between 11 and 13 weeks post partum. Compared with the nonpregnant state, there was a significant fall in systemic vascular resistance, pulmonary vascular resistance, colloid oncotic pressure, and colloid oncotic pressure-pulmonary capillary wedge pressure gradient by the late phase of the third trimester (p < 0.05). Pregnancy was associated with a significant rise in cardiac output and pulse in all patients (p < 0.05). There was no significant change in pulmonary capillary wedge pressure, central venous pressure, left ventricular stroke work index, or mean arterial pressure. Normally the late phase of the third trimester is not associated with hyperdynamic left ventricular function as assessed by the left ventricular stroke work index/pulmonary capillary wedge pressure ratio.

Original languageEnglish (US)
Pages (from-to)1439-1442
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume161
Issue number6 PART 1
DOIs
StatePublished - 1989
Externally publishedYes

Fingerprint

Pulmonary Wedge Pressure
Hemodynamics
Third Pregnancy Trimester
Colloids
Vascular Resistance
Pregnancy
Stroke
Swan-Ganz Catheterization
Pressure
Vascular Access Devices
Central Venous Pressure
Left Ventricular Function
Cardiac Output
Pulse
Arterial Pressure

Keywords

  • critical care
  • Pregnancy
  • pulmonary artery catheter

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Clark, S. L., Cotton, D. B., Lee, W., Bishop, C., Hill, T., Southwick, J., ... Tolley, D. (1989). Central hemodynamic assessment of normal term pregnancy. American Journal of Obstetrics and Gynecology, 161(6 PART 1), 1439-1442. https://doi.org/10.1016/0002-9378(89)90900-9

Central hemodynamic assessment of normal term pregnancy. / Clark, Steven L.; Cotton, David B.; Lee, Wesley; Bishop, Clark; Hill, Tracy; Southwick, James; Pivarnik, James; Spillman, Thomas; DeVore, Greggory R.; Phelan, Jeffrey; Hankins, Gary; Benedetti, Thomas J.; Tolley, Dennis.

In: American Journal of Obstetrics and Gynecology, Vol. 161, No. 6 PART 1, 1989, p. 1439-1442.

Research output: Contribution to journalArticle

Clark, SL, Cotton, DB, Lee, W, Bishop, C, Hill, T, Southwick, J, Pivarnik, J, Spillman, T, DeVore, GR, Phelan, J, Hankins, G, Benedetti, TJ & Tolley, D 1989, 'Central hemodynamic assessment of normal term pregnancy', American Journal of Obstetrics and Gynecology, vol. 161, no. 6 PART 1, pp. 1439-1442. https://doi.org/10.1016/0002-9378(89)90900-9
Clark SL, Cotton DB, Lee W, Bishop C, Hill T, Southwick J et al. Central hemodynamic assessment of normal term pregnancy. American Journal of Obstetrics and Gynecology. 1989;161(6 PART 1):1439-1442. https://doi.org/10.1016/0002-9378(89)90900-9
Clark, Steven L. ; Cotton, David B. ; Lee, Wesley ; Bishop, Clark ; Hill, Tracy ; Southwick, James ; Pivarnik, James ; Spillman, Thomas ; DeVore, Greggory R. ; Phelan, Jeffrey ; Hankins, Gary ; Benedetti, Thomas J. ; Tolley, Dennis. / Central hemodynamic assessment of normal term pregnancy. In: American Journal of Obstetrics and Gynecology. 1989 ; Vol. 161, No. 6 PART 1. pp. 1439-1442.
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