Changes in body temperature markedly affect striatal dopamine release and metabolism

an in vivo study

T. Brannan, J. Martínez-Tica, M. D. Yahr

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Dopamine release and metabolism in the corpus striatum increased markedly when the core body temperature of anesthetized rats was increased from 35 ° to 41 °C while temperatures below 34 ° were associated with a marked attenuation of dopamine release. These observations may have clinical relevance in cases where alterations in body temperature are associated with extrapyramidal dysfunction.

Original languageEnglish (US)
Pages (from-to)193-196
Number of pages4
JournalJournal of Neural Transmission
Volume89
Issue number3
DOIs
StatePublished - Oct 1992
Externally publishedYes

Fingerprint

Body Temperature Changes
Corpus Striatum
Body Temperature
Dopamine
Temperature

Keywords

  • body temperature
  • cerebral microdialysis
  • Dopamine
  • Parkinson's disease

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Changes in body temperature markedly affect striatal dopamine release and metabolism : an in vivo study. / Brannan, T.; Martínez-Tica, J.; Yahr, M. D.

In: Journal of Neural Transmission, Vol. 89, No. 3, 10.1992, p. 193-196.

Research output: Contribution to journalArticle

Brannan, T. ; Martínez-Tica, J. ; Yahr, M. D. / Changes in body temperature markedly affect striatal dopamine release and metabolism : an in vivo study. In: Journal of Neural Transmission. 1992 ; Vol. 89, No. 3. pp. 193-196.
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