TY - JOUR
T1 - Characterization of a dengue virus serotype 1 isolated from a patient in ciudad Juarez, Mexico
AU - Palermo, Pedro M.
AU - de la Mora-Covarrubias, Antonio
AU - Orbegozo, Jeanette
AU - Plante, Jessica
AU - Plante, Kenneth S.
AU - Jimenez-Vega, Florinda
AU - Watts, Douglas M.
N1 - Funding Information:
This research was funded by the Office Research and Sponsored Projects and by a Grant 2U54MD007592 from the National Institutes on Minority Health and Health Disparities (NIMHD), a component of the National Institutes of Health (NIH).
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
PY - 2021/7
Y1 - 2021/7
N2 - Dengue (DEN) is the most important human arboviral disease worldwide. Sporadic outbreaks of DEN have been reported since 1980 in urban communities located along the border in southeast Texas and northern Mexico. Other than the Rio Grande Valley region of TX, autochthonous transmission of DENV has not been reported from any other US border communities. As part of a surveillance program for arthropod-borne viruses in Ciudad Juarez, Mexico, during November 2015, a blood sample was obtained from a female patient who experienced an undifferentiated fever and arthralgia. The plasma of the sample was tested for virus in Vero-76 and C6/36 cells. DENV serotype 1 (DENV-1) was isolated in the C6/36 cells, and nucleotide sequencing of the envelope gene and full genome grouped the DENV-1 isolate in the Central America clade. The patient had not traveled outside of Ciudad Juarez, Mexico, thus suggesting DENV-1 infection was acquired in this community.
AB - Dengue (DEN) is the most important human arboviral disease worldwide. Sporadic outbreaks of DEN have been reported since 1980 in urban communities located along the border in southeast Texas and northern Mexico. Other than the Rio Grande Valley region of TX, autochthonous transmission of DENV has not been reported from any other US border communities. As part of a surveillance program for arthropod-borne viruses in Ciudad Juarez, Mexico, during November 2015, a blood sample was obtained from a female patient who experienced an undifferentiated fever and arthralgia. The plasma of the sample was tested for virus in Vero-76 and C6/36 cells. DENV serotype 1 (DENV-1) was isolated in the C6/36 cells, and nucleotide sequencing of the envelope gene and full genome grouped the DENV-1 isolate in the Central America clade. The patient had not traveled outside of Ciudad Juarez, Mexico, thus suggesting DENV-1 infection was acquired in this community.
KW - Central America clade
KW - Dengue virus
KW - Mexico
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U2 - 10.3390/pathogens10070872
DO - 10.3390/pathogens10070872
M3 - Article
C2 - 34358022
AN - SCOPUS:85111066508
SN - 2076-0817
VL - 10
JO - Pathogens
JF - Pathogens
IS - 7
M1 - 872
ER -