Characterization of a transient unfolding intermediate in a core mutant of γs-Crystallin

Keyphrases

• N-terminal Domain 100%
• Crystallin 100%
• Unfolding Intermediates 100%
• NMR Spectroscopy 33%
• Cataractous Lens 33%
• Cataract 33%
• Fluorescence Spectroscopy 33%
• Via Formation 33%
• Urea 33%
• Structural Proteins 33%
• Neurological Diseases 33%
• Age-related Illnesses 33%
• Protein Aggregates 33%
• Light Scattering 33%
• Temperature Effect 33%
• Concentration-dependent 33%
• Mutant Protein 33%
• Conformational Exchange 33%
• Fibril Formation 33%
• Aggregation Behavior 33%
• Hydrogen-deuterium Exchange 33%
• Denaturants 33%
• Highly Stable 33%
• Scattering Center 33%
• Native Protein 33%
• T2 Relaxation Time 33%
• Intermediate State 33%
• Physiologically Relevant Conditions 33%
• Folded Proteins 33%
• Sequence Variants 33%
• Nonconservative 33%
• Relaxation Dispersion 33%
• Dispersion Experiment 33%
• Nucleation Site 33%
• Carr-Purcell-Meiboom-Gill 33%
• Eye Lens 33%

Biochemistry, Genetics and Molecular Biology

• N-Terminus 100%
• Crystallin 100%
• Structural Protein 33%
• Mutant Protein 33%
• C-Terminus 33%
• Light Scattering 33%
• Hydrogen-Deuterium Exchange 33%
• Nucleation 33%
• Dispersion 33%
• Fluorescence Spectroscopy 33%