Characterization of an acid-inducible sulfatase in Salmonella enterica serovar typhimurium

Seema Das, Swati Singh, Michael McClelland, Steven Forest, Prasad Gyaneshwar

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Sulfatases of enteric bacteria can provide access to heavily sulfated mucosal glycans. In this study, we show that aslA (STM0084) of Salmonella enterica serovar Typhimurium LT2 encodes a sulfatase that requires mildly acidic pH for its expression and activity. AslA is not regulated by sulfur compounds or tyramine but requires the EnvZ-OmpR and PhoPQ regulatory systems, which play an important role in pathogenesis.

Original languageEnglish (US)
Pages (from-to)2092-2095
Number of pages4
JournalApplied and Environmental Microbiology
Volume79
Issue number6
DOIs
StatePublished - Mar 2013
Externally publishedYes

Fingerprint

Sulfatases
arylsulfatase
Salmonella enterica
sulfur compound
Salmonella Typhimurium
Sulfur Compounds
Tyramine
bacterium
Acids
tyramine
acids
acid
Enterobacteriaceae
intestinal microorganisms
Polysaccharides
sulfur
polysaccharides
pathogenesis
Serogroup
salmonella

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Food Science
  • Biotechnology
  • Ecology

Cite this

Characterization of an acid-inducible sulfatase in Salmonella enterica serovar typhimurium. / Das, Seema; Singh, Swati; McClelland, Michael; Forest, Steven; Gyaneshwar, Prasad.

In: Applied and Environmental Microbiology, Vol. 79, No. 6, 03.2013, p. 2092-2095.

Research output: Contribution to journalArticle

Das, Seema ; Singh, Swati ; McClelland, Michael ; Forest, Steven ; Gyaneshwar, Prasad. / Characterization of an acid-inducible sulfatase in Salmonella enterica serovar typhimurium. In: Applied and Environmental Microbiology. 2013 ; Vol. 79, No. 6. pp. 2092-2095.
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