Characterization of an acid-inducible sulfatase in Salmonella enterica serovar typhimurium

Seema Das, Swati Singh, Michael McClelland, Steven Forest, Prasad Gyaneshwar

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Sulfatases of enteric bacteria can provide access to heavily sulfated mucosal glycans. In this study, we show that aslA (STM0084) of Salmonella enterica serovar Typhimurium LT2 encodes a sulfatase that requires mildly acidic pH for its expression and activity. AslA is not regulated by sulfur compounds or tyramine but requires the EnvZ-OmpR and PhoPQ regulatory systems, which play an important role in pathogenesis.

Original languageEnglish (US)
Pages (from-to)2092-2095
Number of pages4
JournalApplied and Environmental Microbiology
Volume79
Issue number6
DOIs
StatePublished - Mar 1 2013

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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