Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008

Gavin J.D. Smith, Dhanasekaran Vijaykrishna, Trevor M. Ellis, Kitman C. Dyrting, Y. H.Connie Leung, Justin Bahl, Chun W. Wong, Kai Huang, Mary K.W. Chow, Lian Duan, Allen S.L. Chan, Li Juan Zhang, Honglin Chen, Geraldine S.M. Luk, J. S.Malik Peiris, Yi Guan

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

From January 2004 through June 2008, surveillance of dead wild birds in Hong Kong, People's Republic of China, periodically detected highly pathogenic avian influenza (HPAI) viruses (H5N1) in individual birds from different species. During this period, no viruses of subtype H5N1 were detected in poultry on farms and in markets in Hong Kong despite intensive surveillance. Thus, these findings in wild birds demonstrate the potential for wild birds to disseminate HPAI viruses (H5N1) to areas otherwise free from the viruses. Genetic and antigenic characterization of 47 HPAI (H5N1) viruses isolated from dead wild birds in Hong Kong showed that these isolates belonged to 2 antigenically distinct virus groups: clades 2.3.4 and 2.3.2. Although research has shown that clade 2.3.4 viruses are established in poultry in Asia, the emergence of clade 2.3.2 viruses in nonpasserine birds from Hong Kong, Japan, and Russia raises the possibility that this virus lineage may have become established in wild birds.

Original languageEnglish (US)
Pages (from-to)402-407
Number of pages6
JournalEmerging infectious diseases
Volume15
Issue number3
DOIs
StatePublished - Mar 1 2009
Externally publishedYes

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Influenza in Birds
Hong Kong
Orthomyxoviridae
Birds
Viruses
H5N1 Subtype Influenza A Virus
Poultry
Russia
China
Japan
Research

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Smith, G. J. D., Vijaykrishna, D., Ellis, T. M., Dyrting, K. C., Leung, Y. H. C., Bahl, J., ... Guan, Y. (2009). Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008. Emerging infectious diseases, 15(3), 402-407. https://doi.org/10.3201/eid1503.081190

Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008. / Smith, Gavin J.D.; Vijaykrishna, Dhanasekaran; Ellis, Trevor M.; Dyrting, Kitman C.; Leung, Y. H.Connie; Bahl, Justin; Wong, Chun W.; Huang, Kai; Chow, Mary K.W.; Duan, Lian; Chan, Allen S.L.; Zhang, Li Juan; Chen, Honglin; Luk, Geraldine S.M.; Peiris, J. S.Malik; Guan, Yi.

In: Emerging infectious diseases, Vol. 15, No. 3, 01.03.2009, p. 402-407.

Research output: Contribution to journalArticle

Smith, GJD, Vijaykrishna, D, Ellis, TM, Dyrting, KC, Leung, YHC, Bahl, J, Wong, CW, Huang, K, Chow, MKW, Duan, L, Chan, ASL, Zhang, LJ, Chen, H, Luk, GSM, Peiris, JSM & Guan, Y 2009, 'Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008', Emerging infectious diseases, vol. 15, no. 3, pp. 402-407. https://doi.org/10.3201/eid1503.081190
Smith GJD, Vijaykrishna D, Ellis TM, Dyrting KC, Leung YHC, Bahl J et al. Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008. Emerging infectious diseases. 2009 Mar 1;15(3):402-407. https://doi.org/10.3201/eid1503.081190
Smith, Gavin J.D. ; Vijaykrishna, Dhanasekaran ; Ellis, Trevor M. ; Dyrting, Kitman C. ; Leung, Y. H.Connie ; Bahl, Justin ; Wong, Chun W. ; Huang, Kai ; Chow, Mary K.W. ; Duan, Lian ; Chan, Allen S.L. ; Zhang, Li Juan ; Chen, Honglin ; Luk, Geraldine S.M. ; Peiris, J. S.Malik ; Guan, Yi. / Characterization of avian influenza viruses A (H5N1) from wild birds, Hong Kong, 2004-2008. In: Emerging infectious diseases. 2009 ; Vol. 15, No. 3. pp. 402-407.
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