Characterization of Leishmania colombiensis sp. n (Kinetoplastida: Trypanosomatidae), a new parasite infecting humans, animals, and phlebotomine sand flies in Colombia and Panama

R. D. Kreutzer, A. Corredor, G. Grimaldi, M. Grogl, E. D. Rowton, D. G. Young, A. Morales, D. McMahon-Pratt, H. Guzman, R. B. Tesh

Research output: Contribution to journalArticle

56 Scopus citations

Abstract

Characterization of Leishmania colombiensis sp.n. is presented, which on the basis of biological and molecular criteria, appears to be a new member of the L. braziliensis complex. A total of nine isolates of the new parasite were made in Colombia and Panama between 1980 and 1986: two from human cases of cutaneous leishmaniasis, six from phlebotomine sand flies, and one from a sloth. Although most closely related to L. lainsoni, L. colombiensis sp.n. is clearly distinguishable from other members of the genus by its reactivity with monoclonal antibodies, isoenzyme electrophoresis, and restriction endonuclease fragment patterns of kinetoplast DNA (k-DNA).

Original languageEnglish (US)
Pages (from-to)662-675
Number of pages14
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume44
Issue number6
DOIs
StatePublished - 1991

ASJC Scopus subject areas

  • Parasitology
  • Virology
  • Infectious Diseases

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