Characterization of Oliveros virus, a new member of the Tacaribe complex (Arenaviridae: Arenavirus)

James N. Mills, Julio G. Barrera Oro, David S. Bressler, James E. Childs, Robert B. Tesh, Jonathan F. Smith, Delia A. Enria, Thomas W. Geisbert, Kelly T. McKee, Michael D. Bowen, C. J. Peters, Peter B. Jahrling

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Oliveros virus is an agent isolated in cell culture from Bolomys obscurus (Rodentia, Muridae, Sigmodontinae) captured on the central Argentine pampa. Oliveros virus was shown to be related to members of the Tacaribe complex of the family Arenaviridae by immunofluorescent antibody (IFA) tests, electrophoretic pattern of viral proteins, and morphology as observed by electron microscopy. It was distinct from 12 other arenaviruses by a combination of plaque-reduction neutralization tests, comparison of endpoint titers among cross-IFA tests, and comparison of viral RNA sequence data. This agent is the third new arenavirus from South America described within the last three years.

Original languageEnglish (US)
Pages (from-to)399-404
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume54
Issue number4
DOIs
StatePublished - Apr 1996
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

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