Characterization of the Changuinola serogroup viruses (Reoviridae: Orbivirus)

A. P A Travassos da Rosa, R. B. Tesh, F. P. Pinheiro, P. H. Peralta, D. L. Knudson

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The antigenic, biological, and chemical properties of 24 selected Changuinola serogroup viruses were examined. The viruses tested were chloroform-resistant, and they were lethal to newborn hamsters after intracerebral inoculation. The prototype Changuinola virus strain (BT-436) replicated in mosquito and sandfly cell cultures. In complement-fixation tests, the viruses were broadly cross-reacting and indistinguishable; but by neutralization test at least 12 distinct serotypes were identified, and by PAGE of double-stranded RNA 22 distinct profiles were found. These data suggest that the Changuinola serogroup may be comprised of a large number of genetically different viruses. A brief review of the natural history of Changuinola serogroup viruses is also given.

Original languageEnglish (US)
Pages (from-to)38-49
Number of pages12
JournalIntervirology
Volume21
Issue number1
StatePublished - 1984
Externally publishedYes

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Orbivirus
Reoviridae
Viruses
Complement Fixation Tests
Psychodidae
Neutralization Tests
Double-Stranded RNA
Chloroform
Culicidae
Natural History
Cricetinae
Cell Culture Techniques
Serogroup

ASJC Scopus subject areas

  • Virology

Cite this

Travassos da Rosa, A. P. A., Tesh, R. B., Pinheiro, F. P., Peralta, P. H., & Knudson, D. L. (1984). Characterization of the Changuinola serogroup viruses (Reoviridae: Orbivirus). Intervirology, 21(1), 38-49.

Characterization of the Changuinola serogroup viruses (Reoviridae : Orbivirus). / Travassos da Rosa, A. P A; Tesh, R. B.; Pinheiro, F. P.; Peralta, P. H.; Knudson, D. L.

In: Intervirology, Vol. 21, No. 1, 1984, p. 38-49.

Research output: Contribution to journalArticle

Travassos da Rosa, APA, Tesh, RB, Pinheiro, FP, Peralta, PH & Knudson, DL 1984, 'Characterization of the Changuinola serogroup viruses (Reoviridae: Orbivirus)', Intervirology, vol. 21, no. 1, pp. 38-49.
Travassos da Rosa APA, Tesh RB, Pinheiro FP, Peralta PH, Knudson DL. Characterization of the Changuinola serogroup viruses (Reoviridae: Orbivirus). Intervirology. 1984;21(1):38-49.
Travassos da Rosa, A. P A ; Tesh, R. B. ; Pinheiro, F. P. ; Peralta, P. H. ; Knudson, D. L. / Characterization of the Changuinola serogroup viruses (Reoviridae : Orbivirus). In: Intervirology. 1984 ; Vol. 21, No. 1. pp. 38-49.
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