Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae)

Gustavo Palacios, Robert B. Tesh, Nazir Savji, Amelia P.A. Travassos da Rosa, Hilda Guzman, Ana Valeria Bussetti, Aaloki Desai, Jason Ladner, Maripaz Sanchez-Seco, W. Ian Lipkin

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27 Scopus citations

Abstract

Genomic and antigenic characterization of members of the Sandfly fever Naples virus (SFNV) complex reveals the presence of five clades that differ in their geographical distribution. Saint Floris and Gordil viruses, both found in Africa, form one clade; Punique, Granada and Massilia viruses, all isolated in the western Mediterranean, constitute a second; Toscana virus, a third; SFNV isolates from Italy, Cyprus, Egypt and India form a fourth; while Tehran virus and a Serbian isolate Yu 8/76, represent a fifth. Interestingly, this last clade appears not to express the second non-structural protein ORF. Karimabad virus, previously classified as a member of the SFNV complex, and Gabek Forest virus are distinct and form a new species complex (named Karimabad) in the Phlebovirus genus. In contrast with the high reassortment frequency observed in some South American phleboviruses, the only virus of the SFNV complex with evidence of reassortment was Granada virus.

Original languageEnglish (US)
Pages (from-to)292-300
Number of pages9
JournalJournal of General Virology
Volume95
Issue numberPART 2
DOIs
StatePublished - Feb 2014

ASJC Scopus subject areas

  • Virology

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    Palacios, G., Tesh, R. B., Savji, N., Travassos da Rosa, A. P. A., Guzman, H., Bussetti, A. V., Desai, A., Ladner, J., Sanchez-Seco, M., & Ian Lipkin, W. (2014). Characterization of the Sandfly fever Naples species complex and description of a new Karimabad species complex (genus Phlebovirus, family Bunyaviridae). Journal of General Virology, 95(PART 2), 292-300. https://doi.org/10.1099/vir.0.056614-0