Characterization of three new insect-specific flaviviruses: Their relationship to the mosquito-borne flavivirus pathogens

Hilda Guzman, Maria Angelica Contreras-Gutierrez, Amelia P.A. Travassos da Rosa, Marcio R.T. Nunes, Jedson F. Cardoso, Vsevolod L. Popov, Katherine I. Young, Chelsea Savit, Thomas G. Wood, Steven G. Widen, Douglas M. Watts, Kathryn A. Hanley, David Perera, Durland Fish, Nikos Vasilakis, Robert B. Tesh

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Three novel insect-specific flaviviruses, isolated from mosquitoes collected in Peru, Malaysia (Sarawak), and the United States, are characterized. The new viruses, designated La Tina, Kampung Karu, and Long Pine Key, respectively, are antigenically and phylogenetically more similar to the mosquito-borne flavivirus pathogens, than to the classical insect-specific viruses like cell fusing agent and Culex flavivirus. The potential implications of this relationship and the possible uses of these and other arbovirus-related insect-specific flaviviruses are reviewed.

Original languageEnglish (US)
Pages (from-to)410-419
Number of pages10
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume98
Issue number2
DOIs
StatePublished - 2018

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

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