Characterization of three new insect-specific flaviviruses

Their relationship to the mosquito-borne flavivirus pathogens

Hilda Guzman, Maria Angelica Contreras-Gutierrez, Amelia P.A. Travassos da Rosa, Marcio R.T. Nunes, Jedson F. Cardoso, Vsevolod Popov, Katherine I. Young, Chelsea Savit, Thomas Wood, Steven Widen, Douglas M. Watts, Kathryn A. Hanley, David Perera, Durland Fish, Nikos Vasilakis, Robert B. Tesh

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Three novel insect-specific flaviviruses, isolated from mosquitoes collected in Peru, Malaysia (Sarawak), and the United States, are characterized. The new viruses, designated La Tina, Kampung Karu, and Long Pine Key, respectively, are antigenically and phylogenetically more similar to the mosquito-borne flavivirus pathogens, than to the classical insect-specific viruses like cell fusing agent and Culex flavivirus. The potential implications of this relationship and the possible uses of these and other arbovirus-related insect-specific flaviviruses are reviewed.

Original languageEnglish (US)
Pages (from-to)410-419
Number of pages10
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume98
Issue number2
DOIs
StatePublished - Jan 1 2018

Fingerprint

Flavivirus
Culicidae
Insects
Malaysia
Insect Viruses
Arboviruses
Culex
Peru
Viruses

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Guzman, H., Contreras-Gutierrez, M. A., Travassos da Rosa, A. P. A., Nunes, M. R. T., Cardoso, J. F., Popov, V., ... Tesh, R. B. (2018). Characterization of three new insect-specific flaviviruses: Their relationship to the mosquito-borne flavivirus pathogens. American Journal of Tropical Medicine and Hygiene, 98(2), 410-419. https://doi.org/10.4269/ajtmh.17-0350

Characterization of three new insect-specific flaviviruses : Their relationship to the mosquito-borne flavivirus pathogens. / Guzman, Hilda; Contreras-Gutierrez, Maria Angelica; Travassos da Rosa, Amelia P.A.; Nunes, Marcio R.T.; Cardoso, Jedson F.; Popov, Vsevolod; Young, Katherine I.; Savit, Chelsea; Wood, Thomas; Widen, Steven; Watts, Douglas M.; Hanley, Kathryn A.; Perera, David; Fish, Durland; Vasilakis, Nikos; Tesh, Robert B.

In: American Journal of Tropical Medicine and Hygiene, Vol. 98, No. 2, 01.01.2018, p. 410-419.

Research output: Contribution to journalArticle

Guzman, H, Contreras-Gutierrez, MA, Travassos da Rosa, APA, Nunes, MRT, Cardoso, JF, Popov, V, Young, KI, Savit, C, Wood, T, Widen, S, Watts, DM, Hanley, KA, Perera, D, Fish, D, Vasilakis, N & Tesh, RB 2018, 'Characterization of three new insect-specific flaviviruses: Their relationship to the mosquito-borne flavivirus pathogens', American Journal of Tropical Medicine and Hygiene, vol. 98, no. 2, pp. 410-419. https://doi.org/10.4269/ajtmh.17-0350
Guzman, Hilda ; Contreras-Gutierrez, Maria Angelica ; Travassos da Rosa, Amelia P.A. ; Nunes, Marcio R.T. ; Cardoso, Jedson F. ; Popov, Vsevolod ; Young, Katherine I. ; Savit, Chelsea ; Wood, Thomas ; Widen, Steven ; Watts, Douglas M. ; Hanley, Kathryn A. ; Perera, David ; Fish, Durland ; Vasilakis, Nikos ; Tesh, Robert B. / Characterization of three new insect-specific flaviviruses : Their relationship to the mosquito-borne flavivirus pathogens. In: American Journal of Tropical Medicine and Hygiene. 2018 ; Vol. 98, No. 2. pp. 410-419.
@article{f70167bb07de4dcc90c113e9c69385da,
title = "Characterization of three new insect-specific flaviviruses: Their relationship to the mosquito-borne flavivirus pathogens",
abstract = "Three novel insect-specific flaviviruses, isolated from mosquitoes collected in Peru, Malaysia (Sarawak), and the United States, are characterized. The new viruses, designated La Tina, Kampung Karu, and Long Pine Key, respectively, are antigenically and phylogenetically more similar to the mosquito-borne flavivirus pathogens, than to the classical insect-specific viruses like cell fusing agent and Culex flavivirus. The potential implications of this relationship and the possible uses of these and other arbovirus-related insect-specific flaviviruses are reviewed.",
author = "Hilda Guzman and Contreras-Gutierrez, {Maria Angelica} and {Travassos da Rosa}, {Amelia P.A.} and Nunes, {Marcio R.T.} and Cardoso, {Jedson F.} and Vsevolod Popov and Young, {Katherine I.} and Chelsea Savit and Thomas Wood and Steven Widen and Watts, {Douglas M.} and Hanley, {Kathryn A.} and David Perera and Durland Fish and Nikos Vasilakis and Tesh, {Robert B.}",
year = "2018",
month = "1",
day = "1",
doi = "10.4269/ajtmh.17-0350",
language = "English (US)",
volume = "98",
pages = "410--419",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "2",

}

TY - JOUR

T1 - Characterization of three new insect-specific flaviviruses

T2 - Their relationship to the mosquito-borne flavivirus pathogens

AU - Guzman, Hilda

AU - Contreras-Gutierrez, Maria Angelica

AU - Travassos da Rosa, Amelia P.A.

AU - Nunes, Marcio R.T.

AU - Cardoso, Jedson F.

AU - Popov, Vsevolod

AU - Young, Katherine I.

AU - Savit, Chelsea

AU - Wood, Thomas

AU - Widen, Steven

AU - Watts, Douglas M.

AU - Hanley, Kathryn A.

AU - Perera, David

AU - Fish, Durland

AU - Vasilakis, Nikos

AU - Tesh, Robert B.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Three novel insect-specific flaviviruses, isolated from mosquitoes collected in Peru, Malaysia (Sarawak), and the United States, are characterized. The new viruses, designated La Tina, Kampung Karu, and Long Pine Key, respectively, are antigenically and phylogenetically more similar to the mosquito-borne flavivirus pathogens, than to the classical insect-specific viruses like cell fusing agent and Culex flavivirus. The potential implications of this relationship and the possible uses of these and other arbovirus-related insect-specific flaviviruses are reviewed.

AB - Three novel insect-specific flaviviruses, isolated from mosquitoes collected in Peru, Malaysia (Sarawak), and the United States, are characterized. The new viruses, designated La Tina, Kampung Karu, and Long Pine Key, respectively, are antigenically and phylogenetically more similar to the mosquito-borne flavivirus pathogens, than to the classical insect-specific viruses like cell fusing agent and Culex flavivirus. The potential implications of this relationship and the possible uses of these and other arbovirus-related insect-specific flaviviruses are reviewed.

UR - http://www.scopus.com/inward/record.url?scp=85041499285&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041499285&partnerID=8YFLogxK

U2 - 10.4269/ajtmh.17-0350

DO - 10.4269/ajtmh.17-0350

M3 - Article

VL - 98

SP - 410

EP - 419

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 2

ER -