Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae

Juliana Abreu Lima, Joaquim Pinto Nunes Neto, Karoline Silva Castro, Amélia Paes de Andrade Travassos da Rosa, Robert Tesh, Márcio Roberto Teixeira Nunes, Vsevolod Popov, Nikos Vasilakis, Hilda Guzman, Steven Widen, Sandro Patroca da Silva, Daniele Barbosa de Almeida Medeiros, Jedson Ferreira Cardoso, Lívia Carício Martins, Raimunda do Socorro da Silva Azevedo, Pedro Fernando da Costa Vasconcelos, Jannifer Oliveira Chiang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Triniti virus (TNTV) has been isolated in Trinidad and Tobago and in Brazil. To date little is known about this virus, which is classified as an ungrouped virus within the family Togaviridae. Here, three isolates of TNTV were characterized both genetically and antigenically. The genome was shown to contain three RNA segments: small (S), medium (M) and large (L). Genome organization, protein sizes and protein motifs were similar to those of viruses in the genus Orthobunyavirus, family Peribunyaviridae. Antigenic reactivity revealed the three TNTV isolates to be closely related, but no serologic cross-reaction with other orthobunyaviruses. Morphological observation by transmission electron microscopy indicated that virus size and symmetry were compatible with those of viruses in the family Peribunyaviridae. Our serological, morphological and molecular results support the taxonomic reclassification of TNTV as a member of the genus Orthobunyavirus, family Peribunyaviridae.

Original languageEnglish (US)
Pages (from-to)137-144
Number of pages8
JournalThe Journal of general virology
Volume100
Issue number2
DOIs
StatePublished - Feb 1 2019

Fingerprint

Viruses
Orthobunyavirus
Togaviridae
Genome
Trinidad and Tobago
Amino Acid Motifs
Cross Reactions
Transmission Electron Microscopy
Brazil
Observation
RNA
Proteins

Keywords

  • arbovirus
  • Peribunyaviridae
  • phylogenetic analysis
  • serologic tests
  • Triniti virus
  • ultrastructure

ASJC Scopus subject areas

  • Virology

Cite this

Lima, J. A., Nunes Neto, J. P., Castro, K. S., Travassos da Rosa, A. P. D. A., Tesh, R., Nunes, M. R. T., ... Chiang, J. O. (2019). Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae. The Journal of general virology, 100(2), 137-144. https://doi.org/10.1099/jgv.0.001196

Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae. / Lima, Juliana Abreu; Nunes Neto, Joaquim Pinto; Castro, Karoline Silva; Travassos da Rosa, Amélia Paes de Andrade; Tesh, Robert; Nunes, Márcio Roberto Teixeira; Popov, Vsevolod; Vasilakis, Nikos; Guzman, Hilda; Widen, Steven; Silva, Sandro Patroca da; Medeiros, Daniele Barbosa de Almeida; Cardoso, Jedson Ferreira; Martins, Lívia Carício; Azevedo, Raimunda do Socorro da Silva; Vasconcelos, Pedro Fernando da Costa; Chiang, Jannifer Oliveira.

In: The Journal of general virology, Vol. 100, No. 2, 01.02.2019, p. 137-144.

Research output: Contribution to journalArticle

Lima, JA, Nunes Neto, JP, Castro, KS, Travassos da Rosa, APDA, Tesh, R, Nunes, MRT, Popov, V, Vasilakis, N, Guzman, H, Widen, S, Silva, SPD, Medeiros, DBDA, Cardoso, JF, Martins, LC, Azevedo, RDSDS, Vasconcelos, PFDC & Chiang, JO 2019, 'Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae', The Journal of general virology, vol. 100, no. 2, pp. 137-144. https://doi.org/10.1099/jgv.0.001196
Lima JA, Nunes Neto JP, Castro KS, Travassos da Rosa APDA, Tesh R, Nunes MRT et al. Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae. The Journal of general virology. 2019 Feb 1;100(2):137-144. https://doi.org/10.1099/jgv.0.001196
Lima, Juliana Abreu ; Nunes Neto, Joaquim Pinto ; Castro, Karoline Silva ; Travassos da Rosa, Amélia Paes de Andrade ; Tesh, Robert ; Nunes, Márcio Roberto Teixeira ; Popov, Vsevolod ; Vasilakis, Nikos ; Guzman, Hilda ; Widen, Steven ; Silva, Sandro Patroca da ; Medeiros, Daniele Barbosa de Almeida ; Cardoso, Jedson Ferreira ; Martins, Lívia Carício ; Azevedo, Raimunda do Socorro da Silva ; Vasconcelos, Pedro Fernando da Costa ; Chiang, Jannifer Oliveira. / Characterization of Triniti virus supports its reclassification in the family Peribunyaviridae. In: The Journal of general virology. 2019 ; Vol. 100, No. 2. pp. 137-144.
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