Chemical burns

Felicia N. Williams, Jong Lee

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Chemical burns represent a small percentage of burn injuries yet up to one third of burn-related deaths. A substantial number of common household and industrial cleaners are responsible for the chemical burns encountered. The pathophysiology of chemical burns, not unlike thermal injuries, is the denaturing of structural proteins, depending on the mechanism of action, concentration, manner and duration of contact, and quantity and phase of agent. Six mechanisms of action are responsible for destruction: reduction, oxidation, corrosion, vesication, desiccation, and protoplasmic poison. Underlying these mechanisms of action are two main categories: acids and alkali compounds. Key to management of chemical injuries is to stop the burning process with copious irrigation, and barring specific treatments outlined in the chapter, the typical burn management of topical agents versus grafting depending on the depth of the injury. Neutralizing agents are contraindicated and can lead to further injury secondary to exothermic reactions.

Original languageEnglish (US)
Title of host publicationTotal Burn Care
Subtitle of host publicationFifth Edition
PublisherElsevier Inc.
Pages408-413.e1
ISBN (Electronic)9780323497428
ISBN (Print)9780323476614
DOIs
StatePublished - Nov 30 2017

Fingerprint

Chemical Burns
Wounds and Injuries
Desiccation
Corrosion
Poisons
Alkalies
Blister
Burns
Hot Temperature
Acids
Proteins

Keywords

  • Acids
  • Alkali
  • Calcium gluconate
  • Chemical burns
  • Coagulation necrosis
  • Denatured proteins
  • Exothermic reaction
  • Hydrofluoric acid
  • Liquefaction necrosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Williams, F. N., & Lee, J. (2017). Chemical burns. In Total Burn Care: Fifth Edition (pp. 408-413.e1). Elsevier Inc.. https://doi.org/10.1016/B978-0-323-47661-4.00039-3

Chemical burns. / Williams, Felicia N.; Lee, Jong.

Total Burn Care: Fifth Edition. Elsevier Inc., 2017. p. 408-413.e1.

Research output: Chapter in Book/Report/Conference proceedingChapter

Williams, FN & Lee, J 2017, Chemical burns. in Total Burn Care: Fifth Edition. Elsevier Inc., pp. 408-413.e1. https://doi.org/10.1016/B978-0-323-47661-4.00039-3
Williams FN, Lee J. Chemical burns. In Total Burn Care: Fifth Edition. Elsevier Inc. 2017. p. 408-413.e1 https://doi.org/10.1016/B978-0-323-47661-4.00039-3
Williams, Felicia N. ; Lee, Jong. / Chemical burns. Total Burn Care: Fifth Edition. Elsevier Inc., 2017. pp. 408-413.e1
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