Chize virus, a new phlebovirus isolated in France from Ixodes (Trichotoixodes) frontalis

C. Chastel, L. Chandler, F. Le Goff, O. Chastel, R. Tesh, R. Shope

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A new phlebovirus (Bunyaviridae family, Phlebovirus genus), provisionally designed Chize virus, was isolated from a nymph of Ixodes (Trichotoixodes) frontalis collected on a wren (Troglodytes troglodytes) found dead in the Chize forest, western France. Chize virus produced a lethal encephalitis in one-day-old mice and cytopathic effect (CPE) in Vero cells. Extracellular particles with a mean diameter of 105 nm with surface spikes characteristic of Uukuniemi (UUK) serogroup viruses were observed in Vero cells. Chize virus reacted in complement-fixation test with several UUK serogroup viruses but was readily distinguished from all registered viruses in the serogroup. I. frontalis is highly specific for birds and unlikely to transmit Chize virus to humans or domestic animals; the pathogenicity of the new virus to wild birds remains to be clarified.

Original languageEnglish (US)
Pages (from-to)279-283
Number of pages5
JournalActa Virologica
Volume43
Issue number5
StatePublished - Oct 1999

Fingerprint

Phlebovirus
Ixodes
France
Viruses
Uukuniemi virus
Vero Cells
Birds
Bunyaviridae
Complement Fixation Tests
Nymph
Songbirds
Domestic Animals
Encephalitis
Virulence

Keywords

  • Bunyavirus
  • Chize virus
  • France
  • Ixodes frontalis
  • Phlebovirus
  • Trichotoixodes frontalis
  • Troglodytes troglodytes
  • Wren

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Chastel, C., Chandler, L., Le Goff, F., Chastel, O., Tesh, R., & Shope, R. (1999). Chize virus, a new phlebovirus isolated in France from Ixodes (Trichotoixodes) frontalis. Acta Virologica, 43(5), 279-283.

Chize virus, a new phlebovirus isolated in France from Ixodes (Trichotoixodes) frontalis. / Chastel, C.; Chandler, L.; Le Goff, F.; Chastel, O.; Tesh, R.; Shope, R.

In: Acta Virologica, Vol. 43, No. 5, 10.1999, p. 279-283.

Research output: Contribution to journalArticle

Chastel, C, Chandler, L, Le Goff, F, Chastel, O, Tesh, R & Shope, R 1999, 'Chize virus, a new phlebovirus isolated in France from Ixodes (Trichotoixodes) frontalis', Acta Virologica, vol. 43, no. 5, pp. 279-283.
Chastel C, Chandler L, Le Goff F, Chastel O, Tesh R, Shope R. Chize virus, a new phlebovirus isolated in France from Ixodes (Trichotoixodes) frontalis. Acta Virologica. 1999 Oct;43(5):279-283.
Chastel, C. ; Chandler, L. ; Le Goff, F. ; Chastel, O. ; Tesh, R. ; Shope, R. / Chize virus, a new phlebovirus isolated in France from Ixodes (Trichotoixodes) frontalis. In: Acta Virologica. 1999 ; Vol. 43, No. 5. pp. 279-283.
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