Abstract
These phylogenetically, phenotypically, and epidemiologically diverse bacteria cause atypical pneumonias (mycoplasmal, chlamydial, and Q fever pneumonia) or pulmonary disease as a component of hematogenous disseminated disease (rickettsial, scrub typhus, ehrlichial, and anaplasmal interstitial pneumonia). They vary from subclinical or self-limited to life-threatening infections. Autopsy and biopsy studies of pulmonary infections caused by Mycoplasma pneumoniae, Chlamydia species, and Coxiella burnetii are rare. Rickettsial, ehrlichial, and anaplasmal infections cause interstitial pneumonias consistent with their obligately intracellular parasitism of endothelial cells (Rickettsia and Orientia), monocytes/macrophages (Ehrlichia chaffeensis), and neutrophils (Anaplasma phagocytophilum).
Original language | English (US) |
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Title of host publication | Pulmonary Pathology |
Subtitle of host publication | A Volume in the Series Foundations in Diagnostic Pathology, Third Edition |
Publisher | Elsevier |
Pages | 344-355 |
Number of pages | 12 |
ISBN (Electronic) | 9780323935487 |
ISBN (Print) | 9780323935715 |
DOIs | |
State | Published - Jan 1 2024 |
Keywords
- chlamydia
- human granulocytotropic anaplasmosis
- human monocytic ehrlichiosis
- mycoplasma
- Q fever
- Rocky Mountain spotted fever
- scrub typhus
ASJC Scopus subject areas
- General Medicine