Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

These phylogenetically, phenotypically, and epidemiologically diverse bacteria cause atypical pneumonias (mycoplasmal, chlamydial, and Q fever pneumonia) or pulmonary disease as a component of hematogenous disseminated disease (rickettsial, scrub typhus, ehrlichial, and anaplasmal interstitial pneumonia). They vary from subclinical or self-limited to life-threatening infections. Autopsy and biopsy studies of pulmonary infections caused by Mycoplasma pneumoniae, Chlamydia species, and Coxiella burnetii are rare. Rickettsial, ehrlichial, and anaplasmal infections cause interstitial pneumonias consistent with their obligately intracellular parasitism of endothelial cells (Rickettsia and Orientia), monocytes/macrophages (Ehrlichia chaffeensis), and neutrophils (Anaplasma phagocytophilum).

Original languageEnglish (US)
Title of host publicationPulmonary Pathology
Subtitle of host publicationA Volume in the Series Foundations in Diagnostic Pathology, Third Edition
PublisherElsevier
Pages344-355
Number of pages12
ISBN (Electronic)9780323935487
ISBN (Print)9780323935715
DOIs
StatePublished - Jan 1 2024

Keywords

  • chlamydia
  • human granulocytotropic anaplasmosis
  • human monocytic ehrlichiosis
  • mycoplasma
  • Q fever
  • Rocky Mountain spotted fever
  • scrub typhus

ASJC Scopus subject areas

  • General Medicine

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