Cholera toxoid boosts serum Escherichia coli antitoxin in humans

D. R. Nalin, A. al-Mahmud, G. Curlin, A. Ahmed, J. Peterson

Research output: Contribution to journalArticle

2 Scopus citations


Sera from individuals vaccinated with a cholera toxoid were tested in order to determine if sera with significant titers of cholera antitoxin could neutralize Escherichia coli thermolabile enterotoxin. Individuals who responded to immunization with significant increases in serum cholera antitoxin titers also showed increases in serum E. coli enterotoxin neutralizing capacity. These findings suggested the possibility that the cholera toxoid vaccine may be useful in preventing disease caused by E. coli.

Original languageEnglish (US)
Pages (from-to)747-749
Number of pages3
JournalInfection and immunity
Issue number4
StatePublished - Dec 1 1974
Externally publishedYes


ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

Cite this

Nalin, D. R., al-Mahmud, A., Curlin, G., Ahmed, A., & Peterson, J. (1974). Cholera toxoid boosts serum Escherichia coli antitoxin in humans. Infection and immunity, 10(4), 747-749.