Cholesterol in serum lipoprotein fractions after spaceflight

C. S. Leach, P. C. Johnson, J. M. Krauhs, Nitza Cintron

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Cholesterol, triglycerides, very low density lipoprotein cholesterol (VLDL-C), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C) were measured in blood samples from 125 crewmembers on the first 24 space shuttle flights. Samples were obtained before, immediately after, and 3-23 days after spaceflight. On landing day, only HDL-C was significantly changed from its preflight level; it had decreased 12.8%. Later in the postflight period, total cholesterol and LDL-C as well as HDL-C decreased significantly. Possible causes of these decreases in estimated cholesterol content of lipoprotein fractions include increased levels of thyroxine during flight and reduced physical activity. The postflight decrease in HDL-C is not considered to have clinical significance for shuttle astronauts, but lipoproteins and apolipoproteins should be measured in blood drawn during longer missions.

Original languageEnglish (US)
Pages (from-to)1034-1037
Number of pages4
JournalAviation Space and Environmental Medicine
Volume59
Issue number11
StatePublished - 1988
Externally publishedYes

Fingerprint

Lipoproteins
Space Flight
Cholesterol
HDL Cholesterol
Serum
LDL Cholesterol
Astronauts
VLDL Cholesterol
Apolipoproteins
Thyroxine
Triglycerides
Blood
Exercise
Space shuttles
Landing

ASJC Scopus subject areas

  • Pollution
  • Medicine(all)
  • Public Health, Environmental and Occupational Health

Cite this

Cholesterol in serum lipoprotein fractions after spaceflight. / Leach, C. S.; Johnson, P. C.; Krauhs, J. M.; Cintron, Nitza.

In: Aviation Space and Environmental Medicine, Vol. 59, No. 11, 1988, p. 1034-1037.

Research output: Contribution to journalArticle

Leach, CS, Johnson, PC, Krauhs, JM & Cintron, N 1988, 'Cholesterol in serum lipoprotein fractions after spaceflight', Aviation Space and Environmental Medicine, vol. 59, no. 11, pp. 1034-1037.
Leach, C. S. ; Johnson, P. C. ; Krauhs, J. M. ; Cintron, Nitza. / Cholesterol in serum lipoprotein fractions after spaceflight. In: Aviation Space and Environmental Medicine. 1988 ; Vol. 59, No. 11. pp. 1034-1037.
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