Choroidal thickness in older patients with central serous chorioretinopathy

Caio V. Regatieri, Eduardo A. Novais, Lauren Branchini, Mehreen Adhi, Emily D. Cole, Ricardo Louzada, Mark Lane, Elias Reichel, Jay S. Duker

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Background: To investigate the choroidal thickness in older patients with central serous chorioretinopathy (CSCR) compared to age-matched normal subjects. Methods: Fifteen patients (30 eyes) with CSCR, all aged ≥60 years, and 21 age-matched normal subjects (21 eyes) underwent high-definition raster scanning using SD-OCT. Both eyes from CSCR patients were included in the analysis. The eyes in patients with CSCR were divided into two groups: active CSCR (17 eyes) if there was foveal-involving subretinal fluid and inactive contralateral eye group (13 eyes). Choroidal thickness was measured from the posterior edge of the retinal pigment epithelium to the choroidal-scleral junction at 500 μm intervals up to 2500 μm temporal and nasal to the fovea (11 locations). Results: The mean age of the patients with CSCR was 68.87 ± 6.83 years (mean ± standard deviation). Reliable measurements of choroidal thickness were obtainable in 70.6 % of eyes examined. The choroid was statistically significantly thicker in eyes with both active CSCR (P < 0.001) and inactive contralateral eyes (P < 0.01) when compared to normal age-matched eyes. The subfoveal choroid was 95 μm (P < 0.01) thicker in eyes with active CSCR (338.05 ± 31.42 μm) compared with normal eyes (243.05 ± 13.39 μm). The subfoveal choroid thickness in the inactive contralateral eyes was numerically greater than normal, and it was not statistically significantly thicker compared to the normal eyes (difference-55.68 μm, P > 0.05). Conclusion: Choroid in older patients with active CSCR was thicker than the choroid in age-matched normal eyes. It is important to consider CSCR as a differential diagnosis of serous retinal detachment in elderly patients with thickened choroid and to consider SD-OCT as an imaging modality by which to evaluate the choroidal thickness.

Original languageEnglish (US)
Article number22
JournalInternational Journal of Retina and Vitreous
Issue number1
StatePublished - Dec 12 2016
Externally publishedYes


  • Central serous chorioretinopathy
  • Choroid
  • Optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology


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