Chronic eosinophilic pneumonia (Carrington's) with increased serum IgE levels. A distinct subset?

Emilio Gonzalez, D. Hayes, V. W. Weedn

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We report our second case of chronic eosinophilic pneumonia (CEP) (Carrington's pneumonia) with elevated serum IgE values and present a review of the literature on this subject. Our present patient, a 55-year-old woman, had classic symptoms of dry cough, weight loss, malaise, dyspnea, night sweats, and fevers. Significant peripheral blood eosinophilia and a right upper lobe infiltrate were present. Glucocorticoid therapy caused prompt resolution of symptoms, as well as disappearance of blood eosinophilia, elevated serum IgE levels, and pulmonary shadowing. The diagnosis of CEP should not be neglected in the classification of the eosinophilic pneumonias with increased serum IgE levels. The increased serum IgE levels, when present in CEP, seem nonspecific and thus may not be useful as a diagnostic adjunct. However, measurement of IgE may be helpful in CEP, as it has been in allergic bronchopulmonary aspergillosis, to guide the dosage and duration of corticosteroid therapy.

Original languageEnglish
Pages (from-to)2622-2624
Number of pages3
JournalArchives of Internal Medicine
Volume148
Issue number12
StatePublished - 1988

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Immunoglobulin E
Serum
Eosinophilia
Allergic Bronchopulmonary Aspergillosis
Pulmonary Eosinophilia
Sweat
Cough
Dyspnea
Glucocorticoids
Weight Loss
Pneumonia
Adrenal Cortex Hormones
Fever
Carrington syndrome
Lung
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

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Chronic eosinophilic pneumonia (Carrington's) with increased serum IgE levels. A distinct subset? / Gonzalez, Emilio; Hayes, D.; Weedn, V. W.

In: Archives of Internal Medicine, Vol. 148, No. 12, 1988, p. 2622-2624.

Research output: Contribution to journalArticle

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