Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil

Felipe Daniel Cardoso; Izabela Mauricio De Rezende; Emanuela Lima Teixeira Barros; Tereza Cristina De Carvalho Souza Garcês; Natalia Ingrid Oliveira Silva; Pedro Augusto Alves; Jefferson Oliveira Soares; Erna Geessien Kroon; Anna Carolina Toledo Da Cunha Pereira; Betânia Paiva Drumond; Gustavo Portela Ferreira

doi:10.1590/s1678-9946201961057

Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil

Felipe Daniel Cardoso, Izabela Mauricio De Rezende, Emanuela Lima Teixeira Barros, Tereza Cristina De Carvalho Souza Garcês, Natalia Ingrid Oliveira Silva, Pedro Augusto Alves, Jefferson Oliveira Soares, Erna Geessien Kroon, Anna Carolina Toledo Da Cunha Pereira, Betânia Paiva Drumond, Gustavo Portela Ferreira

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Chikungunya virus (CHIKV) is an arbovirus that emerged in the Americas in 2013. Infection with CHIKV is symptomatic in most of the cases and patients can develop chronic arthralgia that lasts from months to years in over 40% of the cases. The East-Central-South Africa (ECSA) genotype was introduced in Brazil in 2014, in Bahia State. Here we report the circulation of the CHIKV ECSA genotype in Piaui State, Northeast Brazil, during the years 2016-2017. The phylogenetic analysis revealed a single introduction of this lineage probably in 2015 and its maintenance at least until 2017. This analysis has also demonstrated the proximity of this genotype with isolates from neighboring States, and its partial nucleotide sequence of the viral E1 gene revealed a synapomorphy synonyms. This finding highlights the spread of the ECSA genotype in Brazil and supports its circulation in the Brazilian Northeast.

Original language	English (US)
Article number	e57
Journal	Revista do Instituto de Medicina Tropical de Sao Paulo
Volume	61
DOIs	https://doi.org/10.1590/s1678-9946201961057
State	Published - 2019
Externally published	Yes

Keywords

Alphavirus
Arbovirus
Brazil
Chikungunya virus
E1 gene
ECSA genotype
Epidemiology
Molecular surveillance
Togavirus

ASJC Scopus subject areas

Infectious Diseases

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10.1590/s1678-9946201961057

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Cardoso, F. D., De Rezende, I. M., Teixeira Barros, E. L., De Carvalho Souza Garcês, T. C., Oliveira Silva, N. I., Alves, P. A., Soares, J. O., Kroon, E. G., Da Cunha Pereira, A. C. T., Drumond, B. P., & Ferreira, G. P. (2019). Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil. Revista do Instituto de Medicina Tropical de Sao Paulo, 61, Article e57. https://doi.org/10.1590/s1678-9946201961057

Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil. / Cardoso, Felipe Daniel; De Rezende, Izabela Mauricio; Teixeira Barros, Emanuela Lima et al.
In: Revista do Instituto de Medicina Tropical de Sao Paulo, Vol. 61, e57, 2019.

Research output: Contribution to journal › Article › peer-review

Cardoso, FD, De Rezende, IM, Teixeira Barros, EL, De Carvalho Souza Garcês, TC, Oliveira Silva, NI, Alves, PA, Soares, JO, Kroon, EG, Da Cunha Pereira, ACT, Drumond, BP & Ferreira, GP 2019, 'Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil', Revista do Instituto de Medicina Tropical de Sao Paulo, vol. 61, e57. https://doi.org/10.1590/s1678-9946201961057

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abstract = "Chikungunya virus (CHIKV) is an arbovirus that emerged in the Americas in 2013. Infection with CHIKV is symptomatic in most of the cases and patients can develop chronic arthralgia that lasts from months to years in over 40% of the cases. The East-Central-South Africa (ECSA) genotype was introduced in Brazil in 2014, in Bahia State. Here we report the circulation of the CHIKV ECSA genotype in Piaui State, Northeast Brazil, during the years 2016-2017. The phylogenetic analysis revealed a single introduction of this lineage probably in 2015 and its maintenance at least until 2017. This analysis has also demonstrated the proximity of this genotype with isolates from neighboring States, and its partial nucleotide sequence of the viral E1 gene revealed a synapomorphy synonyms. This finding highlights the spread of the ECSA genotype in Brazil and supports its circulation in the Brazilian Northeast.",

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AU - Teixeira Barros, Emanuela Lima

AU - De Carvalho Souza Garcês, Tereza Cristina

AU - Oliveira Silva, Natalia Ingrid

AU - Alves, Pedro Augusto

AU - Soares, Jefferson Oliveira

AU - Kroon, Erna Geessien

AU - Da Cunha Pereira, Anna Carolina Toledo

AU - Drumond, Betânia Paiva

AU - Ferreira, Gustavo Portela

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AB - Chikungunya virus (CHIKV) is an arbovirus that emerged in the Americas in 2013. Infection with CHIKV is symptomatic in most of the cases and patients can develop chronic arthralgia that lasts from months to years in over 40% of the cases. The East-Central-South Africa (ECSA) genotype was introduced in Brazil in 2014, in Bahia State. Here we report the circulation of the CHIKV ECSA genotype in Piaui State, Northeast Brazil, during the years 2016-2017. The phylogenetic analysis revealed a single introduction of this lineage probably in 2015 and its maintenance at least until 2017. This analysis has also demonstrated the proximity of this genotype with isolates from neighboring States, and its partial nucleotide sequence of the viral E1 gene revealed a synapomorphy synonyms. This finding highlights the spread of the ECSA genotype in Brazil and supports its circulation in the Brazilian Northeast.

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Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil

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Keywords

ASJC Scopus subject areas

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