Clear cell hidradenoma: a mimic of metastatic clear cell tumors.

Keith E. Volmar, Thomas J. Cummings, Wei Hua Wang, Andrew J. Creager, Douglas Tyler, H. Bill Xie

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma. Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern than renal cell carcinoma. Furthermore, immunohistochemical studies can aid in distinguishing the 2 tumors. Knowing the cytologic features of primary skin adnexal neoplasms helps distinguish them from cutaneous metastases, which are more commonly referred for fine-needle aspiration biopsy evaluation. Detailed clinical history, physical findings, and ancillary studies are essential for correct diagnosis and categorization of these tumors. We report the rare case of a patient with renal cell carcinoma who underwent excision of an axillary clear cell hidradenoma, which was clinically suggestive of cutaneous metastatic disease.

Original languageEnglish (US)
JournalArchives of pathology & laboratory medicine
Volume129
Issue number5
StatePublished - 2005
Externally publishedYes

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Acrospiroma
Renal Cell Carcinoma
Neoplasms
Skin
Skin Neoplasms
Fine Needle Biopsy
Skin Diseases
Blood Vessels
Neoplasm Metastasis

Cite this

Volmar, K. E., Cummings, T. J., Wang, W. H., Creager, A. J., Tyler, D., & Xie, H. B. (2005). Clear cell hidradenoma: a mimic of metastatic clear cell tumors. Archives of pathology & laboratory medicine, 129(5).

Clear cell hidradenoma : a mimic of metastatic clear cell tumors. / Volmar, Keith E.; Cummings, Thomas J.; Wang, Wei Hua; Creager, Andrew J.; Tyler, Douglas; Xie, H. Bill.

In: Archives of pathology & laboratory medicine, Vol. 129, No. 5, 2005.

Research output: Contribution to journalArticle

Volmar, KE, Cummings, TJ, Wang, WH, Creager, AJ, Tyler, D & Xie, HB 2005, 'Clear cell hidradenoma: a mimic of metastatic clear cell tumors.', Archives of pathology & laboratory medicine, vol. 129, no. 5.
Volmar, Keith E. ; Cummings, Thomas J. ; Wang, Wei Hua ; Creager, Andrew J. ; Tyler, Douglas ; Xie, H. Bill. / Clear cell hidradenoma : a mimic of metastatic clear cell tumors. In: Archives of pathology & laboratory medicine. 2005 ; Vol. 129, No. 5.
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