Clinical and histologic features of striated muscle hamartoma: Possible relationship to Delleman's syndrome

R. L. Sanchez, Sharon Raimer

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We describe 5 new cases of striated muscle hamartoma (SMH) and review the 7 cases previously described in the literature. Eleven of the 12 patients had single lesions centrally located on the chin (4), near the ala of the nose (3), on the upper chest (3), and on the upper lip (1). Histologically all of the lesions were characterized by a central core containing bundles and individual fibers of skeletal muscle as well as other mesenchymal elements. The muscle fibers penetrated the dermis among numerous folliculo-sebaceous structures. Of the 12 cases of SMH, 3 had other associated congenital anomalies including a cleft lip in 1 patient and a thyroglossal duct sinus in another with single lesions, and preauricular sinuses, low-set ears and bilateral sclerocorneas in the case of multiple SMH. The relationship of SMH with oculocerebrocutaneous syndrome is discussed, and we conclude that at least some of the skin appendages associated with that syndrome are SMH.

Original languageEnglish (US)
Pages (from-to)40-46
Number of pages7
JournalJournal of Cutaneous Pathology
Volume21
Issue number1
StatePublished - 1994

Fingerprint

Hamartoma
Striated Muscle
Chin
Cleft Lip
Skeletal Muscle Fibers
Dermis
Lip
Nose
Ear
Thorax
Oculocerebrocutaneous syndrome
Muscles
Skin

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine

Cite this

Clinical and histologic features of striated muscle hamartoma : Possible relationship to Delleman's syndrome. / Sanchez, R. L.; Raimer, Sharon.

In: Journal of Cutaneous Pathology, Vol. 21, No. 1, 1994, p. 40-46.

Research output: Contribution to journalArticle

@article{e82c186f1640419c9e8f2717fbe7bb42,
title = "Clinical and histologic features of striated muscle hamartoma: Possible relationship to Delleman's syndrome",
abstract = "We describe 5 new cases of striated muscle hamartoma (SMH) and review the 7 cases previously described in the literature. Eleven of the 12 patients had single lesions centrally located on the chin (4), near the ala of the nose (3), on the upper chest (3), and on the upper lip (1). Histologically all of the lesions were characterized by a central core containing bundles and individual fibers of skeletal muscle as well as other mesenchymal elements. The muscle fibers penetrated the dermis among numerous folliculo-sebaceous structures. Of the 12 cases of SMH, 3 had other associated congenital anomalies including a cleft lip in 1 patient and a thyroglossal duct sinus in another with single lesions, and preauricular sinuses, low-set ears and bilateral sclerocorneas in the case of multiple SMH. The relationship of SMH with oculocerebrocutaneous syndrome is discussed, and we conclude that at least some of the skin appendages associated with that syndrome are SMH.",
author = "Sanchez, {R. L.} and Sharon Raimer",
year = "1994",
language = "English (US)",
volume = "21",
pages = "40--46",
journal = "Journal of Cutaneous Pathology",
issn = "0303-6987",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Clinical and histologic features of striated muscle hamartoma

T2 - Possible relationship to Delleman's syndrome

AU - Sanchez, R. L.

AU - Raimer, Sharon

PY - 1994

Y1 - 1994

N2 - We describe 5 new cases of striated muscle hamartoma (SMH) and review the 7 cases previously described in the literature. Eleven of the 12 patients had single lesions centrally located on the chin (4), near the ala of the nose (3), on the upper chest (3), and on the upper lip (1). Histologically all of the lesions were characterized by a central core containing bundles and individual fibers of skeletal muscle as well as other mesenchymal elements. The muscle fibers penetrated the dermis among numerous folliculo-sebaceous structures. Of the 12 cases of SMH, 3 had other associated congenital anomalies including a cleft lip in 1 patient and a thyroglossal duct sinus in another with single lesions, and preauricular sinuses, low-set ears and bilateral sclerocorneas in the case of multiple SMH. The relationship of SMH with oculocerebrocutaneous syndrome is discussed, and we conclude that at least some of the skin appendages associated with that syndrome are SMH.

AB - We describe 5 new cases of striated muscle hamartoma (SMH) and review the 7 cases previously described in the literature. Eleven of the 12 patients had single lesions centrally located on the chin (4), near the ala of the nose (3), on the upper chest (3), and on the upper lip (1). Histologically all of the lesions were characterized by a central core containing bundles and individual fibers of skeletal muscle as well as other mesenchymal elements. The muscle fibers penetrated the dermis among numerous folliculo-sebaceous structures. Of the 12 cases of SMH, 3 had other associated congenital anomalies including a cleft lip in 1 patient and a thyroglossal duct sinus in another with single lesions, and preauricular sinuses, low-set ears and bilateral sclerocorneas in the case of multiple SMH. The relationship of SMH with oculocerebrocutaneous syndrome is discussed, and we conclude that at least some of the skin appendages associated with that syndrome are SMH.

UR - http://www.scopus.com/inward/record.url?scp=0028210034&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028210034&partnerID=8YFLogxK

M3 - Article

C2 - 8188932

AN - SCOPUS:0028210034

VL - 21

SP - 40

EP - 46

JO - Journal of Cutaneous Pathology

JF - Journal of Cutaneous Pathology

SN - 0303-6987

IS - 1

ER -