Clinical and magnetic resonance imaging manifestations of Holmes tremor

Yu Wan Yang, Fang Chia Chang, Chon Haw Tsai, Laura Wu, Chin Song Lu, Chi Chung Kuo, Ming Kuei Lu, Wei Liang Chen, Cheng Chun Lee

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Holmes tremor is a rare symptomatic slow tremor in the proximal parts of the limbs. It may be present at rest or maintenance of a posture, or during the movement of the affected limb. We describe here-in three patients of Holmes tremor with possible etiologies of brainstem infarction and head injury. The intervals between the causal events and the appearance of tremor range from 1 month to 12 months. Magnetic resonance imaging studies reveal hypertrophy of the inferior olivary nucleus in all of the three patients, although only one of them has palatal myoclonus. The surface electromyographic recordings reveal characteristic slow oscillation with frequencies of 3.5 to 4.2 Hz. These features suggest that perturbation of the dentato-rubral-olivary circuitry may play a pivotal role for the generation of Holmes tremor. However, no tight correlation is observed between the presence of inferior olivary nuclear hypertrophy and the appearance of symptomatic palatal myoclonus in the current report.

Original languageEnglish (US)
Pages (from-to)9-15
Number of pages7
JournalActa Neurologica Taiwanica
Volume14
Issue number1
StatePublished - Mar 2005
Externally publishedYes

Fingerprint

Tremor
Magnetic Resonance Imaging
Myoclonus
Hypertrophy
Extremities
Brain Stem Infarctions
Olivary Nucleus
Posture
Craniocerebral Trauma
Maintenance

Keywords

  • Brainstem infarction
  • Dentate-rubral-olivary circuitry
  • Head injury
  • Holmes tremor
  • Inferior olivary nuclear hypertrophy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Yang, Y. W., Chang, F. C., Tsai, C. H., Wu, L., Lu, C. S., Kuo, C. C., ... Lee, C. C. (2005). Clinical and magnetic resonance imaging manifestations of Holmes tremor. Acta Neurologica Taiwanica, 14(1), 9-15.

Clinical and magnetic resonance imaging manifestations of Holmes tremor. / Yang, Yu Wan; Chang, Fang Chia; Tsai, Chon Haw; Wu, Laura; Lu, Chin Song; Kuo, Chi Chung; Lu, Ming Kuei; Chen, Wei Liang; Lee, Cheng Chun.

In: Acta Neurologica Taiwanica, Vol. 14, No. 1, 03.2005, p. 9-15.

Research output: Contribution to journalArticle

Yang, YW, Chang, FC, Tsai, CH, Wu, L, Lu, CS, Kuo, CC, Lu, MK, Chen, WL & Lee, CC 2005, 'Clinical and magnetic resonance imaging manifestations of Holmes tremor', Acta Neurologica Taiwanica, vol. 14, no. 1, pp. 9-15.
Yang YW, Chang FC, Tsai CH, Wu L, Lu CS, Kuo CC et al. Clinical and magnetic resonance imaging manifestations of Holmes tremor. Acta Neurologica Taiwanica. 2005 Mar;14(1):9-15.
Yang, Yu Wan ; Chang, Fang Chia ; Tsai, Chon Haw ; Wu, Laura ; Lu, Chin Song ; Kuo, Chi Chung ; Lu, Ming Kuei ; Chen, Wei Liang ; Lee, Cheng Chun. / Clinical and magnetic resonance imaging manifestations of Holmes tremor. In: Acta Neurologica Taiwanica. 2005 ; Vol. 14, No. 1. pp. 9-15.
@article{aa3e771ceade40aa98e9a9c048cf9118,
title = "Clinical and magnetic resonance imaging manifestations of Holmes tremor",
abstract = "Holmes tremor is a rare symptomatic slow tremor in the proximal parts of the limbs. It may be present at rest or maintenance of a posture, or during the movement of the affected limb. We describe here-in three patients of Holmes tremor with possible etiologies of brainstem infarction and head injury. The intervals between the causal events and the appearance of tremor range from 1 month to 12 months. Magnetic resonance imaging studies reveal hypertrophy of the inferior olivary nucleus in all of the three patients, although only one of them has palatal myoclonus. The surface electromyographic recordings reveal characteristic slow oscillation with frequencies of 3.5 to 4.2 Hz. These features suggest that perturbation of the dentato-rubral-olivary circuitry may play a pivotal role for the generation of Holmes tremor. However, no tight correlation is observed between the presence of inferior olivary nuclear hypertrophy and the appearance of symptomatic palatal myoclonus in the current report.",
keywords = "Brainstem infarction, Dentate-rubral-olivary circuitry, Head injury, Holmes tremor, Inferior olivary nuclear hypertrophy",
author = "Yang, {Yu Wan} and Chang, {Fang Chia} and Tsai, {Chon Haw} and Laura Wu and Lu, {Chin Song} and Kuo, {Chi Chung} and Lu, {Ming Kuei} and Chen, {Wei Liang} and Lee, {Cheng Chun}",
year = "2005",
month = "3",
language = "English (US)",
volume = "14",
pages = "9--15",
journal = "Acta Neurologica Taiwanica",
issn = "1028-768X",
publisher = "Taiwan Neurological Society",
number = "1",

}

TY - JOUR

T1 - Clinical and magnetic resonance imaging manifestations of Holmes tremor

AU - Yang, Yu Wan

AU - Chang, Fang Chia

AU - Tsai, Chon Haw

AU - Wu, Laura

AU - Lu, Chin Song

AU - Kuo, Chi Chung

AU - Lu, Ming Kuei

AU - Chen, Wei Liang

AU - Lee, Cheng Chun

PY - 2005/3

Y1 - 2005/3

N2 - Holmes tremor is a rare symptomatic slow tremor in the proximal parts of the limbs. It may be present at rest or maintenance of a posture, or during the movement of the affected limb. We describe here-in three patients of Holmes tremor with possible etiologies of brainstem infarction and head injury. The intervals between the causal events and the appearance of tremor range from 1 month to 12 months. Magnetic resonance imaging studies reveal hypertrophy of the inferior olivary nucleus in all of the three patients, although only one of them has palatal myoclonus. The surface electromyographic recordings reveal characteristic slow oscillation with frequencies of 3.5 to 4.2 Hz. These features suggest that perturbation of the dentato-rubral-olivary circuitry may play a pivotal role for the generation of Holmes tremor. However, no tight correlation is observed between the presence of inferior olivary nuclear hypertrophy and the appearance of symptomatic palatal myoclonus in the current report.

AB - Holmes tremor is a rare symptomatic slow tremor in the proximal parts of the limbs. It may be present at rest or maintenance of a posture, or during the movement of the affected limb. We describe here-in three patients of Holmes tremor with possible etiologies of brainstem infarction and head injury. The intervals between the causal events and the appearance of tremor range from 1 month to 12 months. Magnetic resonance imaging studies reveal hypertrophy of the inferior olivary nucleus in all of the three patients, although only one of them has palatal myoclonus. The surface electromyographic recordings reveal characteristic slow oscillation with frequencies of 3.5 to 4.2 Hz. These features suggest that perturbation of the dentato-rubral-olivary circuitry may play a pivotal role for the generation of Holmes tremor. However, no tight correlation is observed between the presence of inferior olivary nuclear hypertrophy and the appearance of symptomatic palatal myoclonus in the current report.

KW - Brainstem infarction

KW - Dentate-rubral-olivary circuitry

KW - Head injury

KW - Holmes tremor

KW - Inferior olivary nuclear hypertrophy

UR - http://www.scopus.com/inward/record.url?scp=17144416138&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17144416138&partnerID=8YFLogxK

M3 - Article

C2 - 15835283

AN - SCOPUS:17144416138

VL - 14

SP - 9

EP - 15

JO - Acta Neurologica Taiwanica

JF - Acta Neurologica Taiwanica

SN - 1028-768X

IS - 1

ER -