Clinical approach to the syndromes of viral encephalitis, myelitis, and meningitis

Tracey A. Cho, Robert R. Mckendall

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Viruses are the most common infectious cause of encephalitis, aseptic meningitis, and myelitis. More than 100 viral pathogens have been identified as causing encephalitis. As newer technologies allow for rapid screening for multiple viruses simultaneously, the list of viral central nervous system (CNS) infections is likely to grow. Numerous non-viral infections and non-infectious processes can mimic viral CNS infection. A systematic approach to viral CNS disease therefore must take into account viral factors, including tropism for certain CNS structures, host factors, including immune status and exposure risk, and targeted testing aimed at the most serious and most likely etiologies. While treatment for most viral CNS infections is supportive, certain inflammatory CNS diseases have drastically different outcomes depending on appropriate and timely treatment and therefore must be distinguished quickly from other viral causes.

Original languageEnglish (US)
Pages (from-to)89-121
Number of pages33
JournalHandbook of Clinical Neurology
Volume123
DOIs
StatePublished - 2014

Fingerprint

Central Nervous System Viral Diseases
Viral Meningitis
Viral Encephalitis
Myelitis
Viruses
Aseptic Meningitis
Tropism
Central Nervous System Diseases
Immunologic Factors
Encephalitis
Central Nervous System
Technology
Therapeutics
Infection

Keywords

  • Encephalitis
  • Encephalopathy
  • Meningitis
  • Myelitis
  • Myelopathy
  • Viral

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Clinical approach to the syndromes of viral encephalitis, myelitis, and meningitis. / Cho, Tracey A.; Mckendall, Robert R.

In: Handbook of Clinical Neurology, Vol. 123, 2014, p. 89-121.

Research output: Contribution to journalArticle

Cho, Tracey A. ; Mckendall, Robert R. / Clinical approach to the syndromes of viral encephalitis, myelitis, and meningitis. In: Handbook of Clinical Neurology. 2014 ; Vol. 123. pp. 89-121.
@article{41d39cbacaab4b809e0f9f4704966502,
title = "Clinical approach to the syndromes of viral encephalitis, myelitis, and meningitis",
abstract = "Viruses are the most common infectious cause of encephalitis, aseptic meningitis, and myelitis. More than 100 viral pathogens have been identified as causing encephalitis. As newer technologies allow for rapid screening for multiple viruses simultaneously, the list of viral central nervous system (CNS) infections is likely to grow. Numerous non-viral infections and non-infectious processes can mimic viral CNS infection. A systematic approach to viral CNS disease therefore must take into account viral factors, including tropism for certain CNS structures, host factors, including immune status and exposure risk, and targeted testing aimed at the most serious and most likely etiologies. While treatment for most viral CNS infections is supportive, certain inflammatory CNS diseases have drastically different outcomes depending on appropriate and timely treatment and therefore must be distinguished quickly from other viral causes.",
keywords = "Encephalitis, Encephalopathy, Meningitis, Myelitis, Myelopathy, Viral",
author = "Cho, {Tracey A.} and Mckendall, {Robert R.}",
year = "2014",
doi = "10.1016/B978-0-444-53488-0.00004-3",
language = "English (US)",
volume = "123",
pages = "89--121",
journal = "Handbook of Clinical Neurology",
issn = "0072-9752",
publisher = "Elsevier",

}

TY - JOUR

T1 - Clinical approach to the syndromes of viral encephalitis, myelitis, and meningitis

AU - Cho, Tracey A.

AU - Mckendall, Robert R.

PY - 2014

Y1 - 2014

N2 - Viruses are the most common infectious cause of encephalitis, aseptic meningitis, and myelitis. More than 100 viral pathogens have been identified as causing encephalitis. As newer technologies allow for rapid screening for multiple viruses simultaneously, the list of viral central nervous system (CNS) infections is likely to grow. Numerous non-viral infections and non-infectious processes can mimic viral CNS infection. A systematic approach to viral CNS disease therefore must take into account viral factors, including tropism for certain CNS structures, host factors, including immune status and exposure risk, and targeted testing aimed at the most serious and most likely etiologies. While treatment for most viral CNS infections is supportive, certain inflammatory CNS diseases have drastically different outcomes depending on appropriate and timely treatment and therefore must be distinguished quickly from other viral causes.

AB - Viruses are the most common infectious cause of encephalitis, aseptic meningitis, and myelitis. More than 100 viral pathogens have been identified as causing encephalitis. As newer technologies allow for rapid screening for multiple viruses simultaneously, the list of viral central nervous system (CNS) infections is likely to grow. Numerous non-viral infections and non-infectious processes can mimic viral CNS infection. A systematic approach to viral CNS disease therefore must take into account viral factors, including tropism for certain CNS structures, host factors, including immune status and exposure risk, and targeted testing aimed at the most serious and most likely etiologies. While treatment for most viral CNS infections is supportive, certain inflammatory CNS diseases have drastically different outcomes depending on appropriate and timely treatment and therefore must be distinguished quickly from other viral causes.

KW - Encephalitis

KW - Encephalopathy

KW - Meningitis

KW - Myelitis

KW - Myelopathy

KW - Viral

UR - http://www.scopus.com/inward/record.url?scp=84903982964&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84903982964&partnerID=8YFLogxK

U2 - 10.1016/B978-0-444-53488-0.00004-3

DO - 10.1016/B978-0-444-53488-0.00004-3

M3 - Article

VL - 123

SP - 89

EP - 121

JO - Handbook of Clinical Neurology

JF - Handbook of Clinical Neurology

SN - 0072-9752

ER -