Clinical spectrum of acute otitis media complicating upper respiratory tract viral infection

Stella U. Kalu, Ramona S. Ataya, David P. McCormick, Janak Patel, Krystal Revai, Tasnee Chonmaitree

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Background: Acute otitis media (AOM) often occurs as a complication of upper respiratory tract infection (URI). Objective: To describe otoscopic findings during URI, the full clinical spectrum of AOM, and outcome of cases managed with watchful waiting. Methods: In a prospective study of 294 healthy children (6 months-3 years), characteristics of AOM complicating URI were studied. Otoscopic findings were categorized by tympanic membrane (TM) position, color, translucency, and mobility. Otoscopic score was assigned based on McCormick otoscopy scale (OS)-8 scale. Results: During days 1 to 7 of URI, otoscopic findings at 1114 visits were consistent with AOM in 22%; myringitis (inflamed TM, no fluid) was diagnosed in 7%. In AOM episodes diagnosed within 28 days of URI onset, TM position was described as: nonbulging (19%), mild bulging (45%), bulging (29%), and TM perforation occurred in (6%). OS-8 scale showed mild TM inflammation (OS, 2-3) in 6%, moderate (OS, 4-5) in 59%, and severe (OS, 6-8) in 35%. In 54% of 126 bilateral AOM episodes, inflammation of both TMs was at different stages. Of 28 cases of nonsevere AOM managed with watchful waiting, 4 progressed and 3 later required an antibiotic. Conclusions: AOM is a spectrum of infection that may present at various stages, even in the same child with bilateral disease. During URI, otoscopic changes are observed from the first day of onset. Understanding the wide clinical spectrum of AOM is needed to help with future clinical trial design and development of a scoring system to establish treatment criteria that will minimize antibiotic use.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalPediatric Infectious Disease Journal
Volume30
Issue number2
DOIs
StatePublished - Feb 2011

Fingerprint

Otitis Media
Virus Diseases
Respiratory Tract Infections
Otoscopy
Tympanic Membrane
Watchful Waiting
Tympanic Membrane Perforation
Anti-Bacterial Agents
Inflammation
Color
Clinical Trials
Prospective Studies
Infection

Keywords

  • acute otitis media
  • clinical spectrum
  • myringitis
  • upper respiratory tract infection
  • viral respiratory infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

Cite this

Clinical spectrum of acute otitis media complicating upper respiratory tract viral infection. / Kalu, Stella U.; Ataya, Ramona S.; McCormick, David P.; Patel, Janak; Revai, Krystal; Chonmaitree, Tasnee.

In: Pediatric Infectious Disease Journal, Vol. 30, No. 2, 02.2011, p. 95-99.

Research output: Contribution to journalArticle

Kalu, Stella U. ; Ataya, Ramona S. ; McCormick, David P. ; Patel, Janak ; Revai, Krystal ; Chonmaitree, Tasnee. / Clinical spectrum of acute otitis media complicating upper respiratory tract viral infection. In: Pediatric Infectious Disease Journal. 2011 ; Vol. 30, No. 2. pp. 95-99.
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abstract = "Background: Acute otitis media (AOM) often occurs as a complication of upper respiratory tract infection (URI). Objective: To describe otoscopic findings during URI, the full clinical spectrum of AOM, and outcome of cases managed with watchful waiting. Methods: In a prospective study of 294 healthy children (6 months-3 years), characteristics of AOM complicating URI were studied. Otoscopic findings were categorized by tympanic membrane (TM) position, color, translucency, and mobility. Otoscopic score was assigned based on McCormick otoscopy scale (OS)-8 scale. Results: During days 1 to 7 of URI, otoscopic findings at 1114 visits were consistent with AOM in 22{\%}; myringitis (inflamed TM, no fluid) was diagnosed in 7{\%}. In AOM episodes diagnosed within 28 days of URI onset, TM position was described as: nonbulging (19{\%}), mild bulging (45{\%}), bulging (29{\%}), and TM perforation occurred in (6{\%}). OS-8 scale showed mild TM inflammation (OS, 2-3) in 6{\%}, moderate (OS, 4-5) in 59{\%}, and severe (OS, 6-8) in 35{\%}. In 54{\%} of 126 bilateral AOM episodes, inflammation of both TMs was at different stages. Of 28 cases of nonsevere AOM managed with watchful waiting, 4 progressed and 3 later required an antibiotic. Conclusions: AOM is a spectrum of infection that may present at various stages, even in the same child with bilateral disease. During URI, otoscopic changes are observed from the first day of onset. Understanding the wide clinical spectrum of AOM is needed to help with future clinical trial design and development of a scoring system to establish treatment criteria that will minimize antibiotic use.",
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