Cloning, structure and evolution of the enhancer of split groucho and related genes from human, mouse, alligator, xenopus and nematode

Barun K. Choudhury; Hideyuki Mannen; Farida S. Sharief; Esther W. Hou; Steven S.L. Li

Cloning, structure and evolution of the enhancer of split groucho and related genes from human, mouse, alligator, xenopus and nematode

Barun K. Choudhury, Hideyuki Mannen, Farida S. Sharief, Esther W. Hou, Steven S.L. Li

Research output: Contribution to journal › Article › peer-review

Abstract

The cDNAs encoding the enhancer of split groucho (ESG) and its related amino-terminal (AES) proteins were isolated and sequenced from human, mouse, alligator, Xenopus and nematode. The ESG proteins consist of 771 amino acids, while the AES proteins contain 197 amino acids. The AES proteins were found to exhibit approximately 50% identity to the amino-terminal region of Drosophila enhancer of split groucho protein. The expression of ESG and AES transcripts have been investigated from various tissues and/or developmental stages of human, mouse and Xenopus. The evolutionary relationships among these AES and ESG genes were analyzed. These AES proteins from Xenopus, Alligator, mouse, rat and human are clustered into a group, while the ESG proteins from nematode, Drosophila, Xenopus, mouse, rat and human are clustered into a separate group.

Original language	English (US)
Pages (from-to)	A1154
Journal	FASEB Journal
Volume	10
Issue number	6
State	Published - 1996
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Biochemistry
Molecular Biology
Genetics

Cite this

@article{dc20e4282a2a43b7961395b544cc0c8d,

title = "Cloning, structure and evolution of the enhancer of split groucho and related genes from human, mouse, alligator, xenopus and nematode",

abstract = "The cDNAs encoding the enhancer of split groucho (ESG) and its related amino-terminal (AES) proteins were isolated and sequenced from human, mouse, alligator, Xenopus and nematode. The ESG proteins consist of 771 amino acids, while the AES proteins contain 197 amino acids. The AES proteins were found to exhibit approximately 50% identity to the amino-terminal region of Drosophila enhancer of split groucho protein. The expression of ESG and AES transcripts have been investigated from various tissues and/or developmental stages of human, mouse and Xenopus. The evolutionary relationships among these AES and ESG genes were analyzed. These AES proteins from Xenopus, Alligator, mouse, rat and human are clustered into a group, while the ESG proteins from nematode, Drosophila, Xenopus, mouse, rat and human are clustered into a separate group.",

author = "Choudhury, {Barun K.} and Hideyuki Mannen and Sharief, {Farida S.} and Hou, {Esther W.} and Li, {Steven S.L.}",

year = "1996",

language = "English (US)",

volume = "10",

pages = "A1154",

journal = "FASEB Journal",

issn = "0892-6638",

publisher = "FASEB",

number = "6",

}

TY - JOUR

T1 - Cloning, structure and evolution of the enhancer of split groucho and related genes from human, mouse, alligator, xenopus and nematode

AU - Choudhury, Barun K.

AU - Mannen, Hideyuki

AU - Sharief, Farida S.

AU - Hou, Esther W.

AU - Li, Steven S.L.

PY - 1996

Y1 - 1996

N2 - The cDNAs encoding the enhancer of split groucho (ESG) and its related amino-terminal (AES) proteins were isolated and sequenced from human, mouse, alligator, Xenopus and nematode. The ESG proteins consist of 771 amino acids, while the AES proteins contain 197 amino acids. The AES proteins were found to exhibit approximately 50% identity to the amino-terminal region of Drosophila enhancer of split groucho protein. The expression of ESG and AES transcripts have been investigated from various tissues and/or developmental stages of human, mouse and Xenopus. The evolutionary relationships among these AES and ESG genes were analyzed. These AES proteins from Xenopus, Alligator, mouse, rat and human are clustered into a group, while the ESG proteins from nematode, Drosophila, Xenopus, mouse, rat and human are clustered into a separate group.

AB - The cDNAs encoding the enhancer of split groucho (ESG) and its related amino-terminal (AES) proteins were isolated and sequenced from human, mouse, alligator, Xenopus and nematode. The ESG proteins consist of 771 amino acids, while the AES proteins contain 197 amino acids. The AES proteins were found to exhibit approximately 50% identity to the amino-terminal region of Drosophila enhancer of split groucho protein. The expression of ESG and AES transcripts have been investigated from various tissues and/or developmental stages of human, mouse and Xenopus. The evolutionary relationships among these AES and ESG genes were analyzed. These AES proteins from Xenopus, Alligator, mouse, rat and human are clustered into a group, while the ESG proteins from nematode, Drosophila, Xenopus, mouse, rat and human are clustered into a separate group.

UR - http://www.scopus.com/inward/record.url?scp=33748890875&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33748890875&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33748890875

SN - 0892-6638

VL - 10

SP - A1154

JO - FASEB Journal

JF - FASEB Journal

IS - 6

ER -

Cloning, structure and evolution of the enhancer of split groucho and related genes from human, mouse, alligator, xenopus and nematode

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this