Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films

Vladimir A. Sinani, Dmitry S. Koktysh, Bo Geon Yun, Robert L. Matts, Todd C. Pappas, Massoud Motamedi, Stephanie N. Thomas, Nicholas A. Kotov

Research output: Contribution to journalArticle

153 Scopus citations

Abstract

Nanostructured thin films fabricated from semiconductor nanoparticles (NPs) are of great interest for biomedical applications, but NP materials based on heavy metals can be cytotoxic. In this work, the preparation of semiconductor NPs followed the protocol of layer-by-layer (LBL) assembly, which alleviates this problem. Collagen/poly(acrylic acid) bilayers were added to CdTe/ polycation LBL films to produce porous collagen bilayers. Such stratified multilayer systems showed successful cell attachment and survival while native NP films were strongly cytotoxic.

Original languageEnglish (US)
Pages (from-to)1177-1182
Number of pages6
JournalNano Letters
Volume3
Issue number9
DOIs
StatePublished - Sep 1 2003

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

Fingerprint Dive into the research topics of 'Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films'. Together they form a unique fingerprint.

  • Cite this

    Sinani, V. A., Koktysh, D. S., Yun, B. G., Matts, R. L., Pappas, T. C., Motamedi, M., Thomas, S. N., & Kotov, N. A. (2003). Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films. Nano Letters, 3(9), 1177-1182. https://doi.org/10.1021/nl0255045