Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films

Vladimir A. Sinani, Dmitry S. Koktysh, Bo Geon Yun, Robert L. Matts, Todd C. Pappas, Massoud Motamedi, Stephanie N. Thomas, Nicholas A. Kotov

Research output: Contribution to journalArticle

150 Citations (Scopus)

Abstract

Nanostructured thin films fabricated from semiconductor nanoparticles (NPs) are of great interest for biomedical applications, but NP materials based on heavy metals can be cytotoxic. In this work, the preparation of semiconductor NPs followed the protocol of layer-by-layer (LBL) assembly, which alleviates this problem. Collagen/poly(acrylic acid) bilayers were added to CdTe/ polycation LBL films to produce porous collagen bilayers. Such stratified multilayer systems showed successful cell attachment and survival while native NP films were strongly cytotoxic.

Original languageEnglish (US)
Pages (from-to)1177-1182
Number of pages6
JournalNano Letters
Volume3
Issue number9
DOIs
StatePublished - Sep 1 2003

Fingerprint

biocompatibility
strata
collagens
Biocompatibility
Collagen
Semiconductor materials
Nanoparticles
coatings
Coatings
nanoparticles
carbopol 940
acrylic acid
heavy metals
Heavy Metals
Heavy metals
Acrylics
attachment
Multilayers
assembly
Thin films

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Sinani, V. A., Koktysh, D. S., Yun, B. G., Matts, R. L., Pappas, T. C., Motamedi, M., ... Kotov, N. A. (2003). Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films. Nano Letters, 3(9), 1177-1182. https://doi.org/10.1021/nl0255045

Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films. / Sinani, Vladimir A.; Koktysh, Dmitry S.; Yun, Bo Geon; Matts, Robert L.; Pappas, Todd C.; Motamedi, Massoud; Thomas, Stephanie N.; Kotov, Nicholas A.

In: Nano Letters, Vol. 3, No. 9, 01.09.2003, p. 1177-1182.

Research output: Contribution to journalArticle

Sinani, VA, Koktysh, DS, Yun, BG, Matts, RL, Pappas, TC, Motamedi, M, Thomas, SN & Kotov, NA 2003, 'Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films', Nano Letters, vol. 3, no. 9, pp. 1177-1182. https://doi.org/10.1021/nl0255045
Sinani, Vladimir A. ; Koktysh, Dmitry S. ; Yun, Bo Geon ; Matts, Robert L. ; Pappas, Todd C. ; Motamedi, Massoud ; Thomas, Stephanie N. ; Kotov, Nicholas A. / Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films. In: Nano Letters. 2003 ; Vol. 3, No. 9. pp. 1177-1182.
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