Colonic motor response to a meal in dogs

S. K. Sarna, I. M. Lang

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

We investigated the effects of ingestion of a meal on colonic motor activity in six conscious dogs, each instrumented with seven strain-gauge transducers to record circular muscle contractions. A 1,300-kcal meal was given after a 4-h control recording. The postprandial period of 8 h was subdivided into an early period lasting 2 h and a late period lasting 6 h. The ingestion of the meal did not disrupt the colonic migrating myoelectric complexes (CMMCs) but prolonged their cycle length in the early postprandial period. The cycle length was not different from the control during the late postprandial period. The mean and total duration of contractile activity per hour increased significantly during the early postprandial period in the distal colon but not in the proximal or the middle colon. During the late postprandial period the mean and total duration of contractile activity per hour increased significantly throughout the colon. Giant migrating contractions occurred rarely during the 8-h postprandial period. We conclude that different parts of the colon respond to the ingestion of a meal in different ways. The responses also depends on whether the fresh digesta has reached the colon. The late postprandial response is likely to be due to the entry of fresh digesta into the colon.

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Gastrointestinal and Liver Physiology
Volume257
Issue number5
StatePublished - 1989
Externally publishedYes

Fingerprint

Postprandial Period
Meals
Colon
Dogs
Eating
Migrating Myoelectric Complexes
Muscle Contraction
Transducers
Motor Activity

Keywords

  • Electrical control activity
  • Gastrocolonic reflex
  • Gastrocolonic response
  • Giant migrating contractions
  • Migrating motor complex
  • Motility
  • Slow wave

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

Cite this

Colonic motor response to a meal in dogs. / Sarna, S. K.; Lang, I. M.

In: American Journal of Physiology - Gastrointestinal and Liver Physiology, Vol. 257, No. 5, 1989.

Research output: Contribution to journalArticle

@article{5d2ab779092740b6a6673d980a567b39,
title = "Colonic motor response to a meal in dogs",
abstract = "We investigated the effects of ingestion of a meal on colonic motor activity in six conscious dogs, each instrumented with seven strain-gauge transducers to record circular muscle contractions. A 1,300-kcal meal was given after a 4-h control recording. The postprandial period of 8 h was subdivided into an early period lasting 2 h and a late period lasting 6 h. The ingestion of the meal did not disrupt the colonic migrating myoelectric complexes (CMMCs) but prolonged their cycle length in the early postprandial period. The cycle length was not different from the control during the late postprandial period. The mean and total duration of contractile activity per hour increased significantly during the early postprandial period in the distal colon but not in the proximal or the middle colon. During the late postprandial period the mean and total duration of contractile activity per hour increased significantly throughout the colon. Giant migrating contractions occurred rarely during the 8-h postprandial period. We conclude that different parts of the colon respond to the ingestion of a meal in different ways. The responses also depends on whether the fresh digesta has reached the colon. The late postprandial response is likely to be due to the entry of fresh digesta into the colon.",
keywords = "Electrical control activity, Gastrocolonic reflex, Gastrocolonic response, Giant migrating contractions, Migrating motor complex, Motility, Slow wave",
author = "Sarna, {S. K.} and Lang, {I. M.}",
year = "1989",
language = "English (US)",
volume = "257",
journal = "American Journal of Physiology - Endocrinology and Metabolism",
issn = "0193-1849",
publisher = "American Physiological Society",
number = "5",

}

TY - JOUR

T1 - Colonic motor response to a meal in dogs

AU - Sarna, S. K.

AU - Lang, I. M.

PY - 1989

Y1 - 1989

N2 - We investigated the effects of ingestion of a meal on colonic motor activity in six conscious dogs, each instrumented with seven strain-gauge transducers to record circular muscle contractions. A 1,300-kcal meal was given after a 4-h control recording. The postprandial period of 8 h was subdivided into an early period lasting 2 h and a late period lasting 6 h. The ingestion of the meal did not disrupt the colonic migrating myoelectric complexes (CMMCs) but prolonged their cycle length in the early postprandial period. The cycle length was not different from the control during the late postprandial period. The mean and total duration of contractile activity per hour increased significantly during the early postprandial period in the distal colon but not in the proximal or the middle colon. During the late postprandial period the mean and total duration of contractile activity per hour increased significantly throughout the colon. Giant migrating contractions occurred rarely during the 8-h postprandial period. We conclude that different parts of the colon respond to the ingestion of a meal in different ways. The responses also depends on whether the fresh digesta has reached the colon. The late postprandial response is likely to be due to the entry of fresh digesta into the colon.

AB - We investigated the effects of ingestion of a meal on colonic motor activity in six conscious dogs, each instrumented with seven strain-gauge transducers to record circular muscle contractions. A 1,300-kcal meal was given after a 4-h control recording. The postprandial period of 8 h was subdivided into an early period lasting 2 h and a late period lasting 6 h. The ingestion of the meal did not disrupt the colonic migrating myoelectric complexes (CMMCs) but prolonged their cycle length in the early postprandial period. The cycle length was not different from the control during the late postprandial period. The mean and total duration of contractile activity per hour increased significantly during the early postprandial period in the distal colon but not in the proximal or the middle colon. During the late postprandial period the mean and total duration of contractile activity per hour increased significantly throughout the colon. Giant migrating contractions occurred rarely during the 8-h postprandial period. We conclude that different parts of the colon respond to the ingestion of a meal in different ways. The responses also depends on whether the fresh digesta has reached the colon. The late postprandial response is likely to be due to the entry of fresh digesta into the colon.

KW - Electrical control activity

KW - Gastrocolonic reflex

KW - Gastrocolonic response

KW - Giant migrating contractions

KW - Migrating motor complex

KW - Motility

KW - Slow wave

UR - http://www.scopus.com/inward/record.url?scp=0024377211&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024377211&partnerID=8YFLogxK

M3 - Article

C2 - 2596613

AN - SCOPUS:0024377211

VL - 257

JO - American Journal of Physiology - Endocrinology and Metabolism

JF - American Journal of Physiology - Endocrinology and Metabolism

SN - 0193-1849

IS - 5

ER -