Colonization and infection associated with Malassezia and Candida species in a neonatal unit

Karen Shattuck, C. K. Cochran, R. J. Zabransky, L. Pasarell, Jay Davis, Michael Malloy

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The objectives of this study were to determine, in neonates of < 1250 g birthweight (N = 57), the initial time of skin colonization by Malassezia furfur, rate of colonization by Candida spp., and whether skin colonization by these yeasts was predictive of central line colonization or fungaemia. By age two weeks, 51% of neonates were culture-positive for M. furfur on umbilical or groin skin. During hospitalization, positive skin cultures for M. furfur or Candida spp. were obtained in 70% and 37% of neonates, respectively. Risk factors associated with positive skin cultures were mechanical ventilation and three or more episodes of suspected sepsis. Eight of the 52 infants with central venous catheters, had positive blood cultures withdrawn from the lines; five (62%) of these had positive skin surveillance cultures. Although positive skin cultures for M. furfur, Candida spp., or both were commonly observed in this population, they were not predictive of positive central line cultures or systemic illness.

Original languageEnglish (US)
Pages (from-to)123-129
Number of pages7
JournalJournal of Hospital Infection
Volume34
Issue number2
DOIs
StatePublished - Oct 1996

Fingerprint

Malassezia
Candida
Skin
Infection
Newborn Infant
Fungemia
Umbilicus
Central Venous Catheters
Groin
Artificial Respiration
Sepsis
Hospitalization
Yeasts

Keywords

  • Candida
  • Central venous catheters
  • Malassezia furfur
  • Premature neonates

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Microbiology
  • Parasitology
  • Virology
  • Immunology and Allergy
  • Infectious Diseases

Cite this

Colonization and infection associated with Malassezia and Candida species in a neonatal unit. / Shattuck, Karen; Cochran, C. K.; Zabransky, R. J.; Pasarell, L.; Davis, Jay; Malloy, Michael.

In: Journal of Hospital Infection, Vol. 34, No. 2, 10.1996, p. 123-129.

Research output: Contribution to journalArticle

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AB - The objectives of this study were to determine, in neonates of < 1250 g birthweight (N = 57), the initial time of skin colonization by Malassezia furfur, rate of colonization by Candida spp., and whether skin colonization by these yeasts was predictive of central line colonization or fungaemia. By age two weeks, 51% of neonates were culture-positive for M. furfur on umbilical or groin skin. During hospitalization, positive skin cultures for M. furfur or Candida spp. were obtained in 70% and 37% of neonates, respectively. Risk factors associated with positive skin cultures were mechanical ventilation and three or more episodes of suspected sepsis. Eight of the 52 infants with central venous catheters, had positive blood cultures withdrawn from the lines; five (62%) of these had positive skin surveillance cultures. Although positive skin cultures for M. furfur, Candida spp., or both were commonly observed in this population, they were not predictive of positive central line cultures or systemic illness.

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