Colonoscopy and Flexible Sigmoidoscopy in Colorectal Cancer Screening and Surveillance

Juliana Yang, John H. Kwon

Research output: Contribution to journalReview articlepeer-review


Since the invention of endoscopy in the 1800s, colonoscopy and flexible sigmoidoscopy have evolved into important tools in the diagnosis and treatment of lower gastrointestinal luminal diseases. These two modalities along with biochemical markers and widespread implementation of colorectal cancer (CRC) screening are responsible for the overall downtrend of CRC. However, this downward trend is not as robustly reflected in the right-sided CRC. It is thought that flat lesions in the right colon (sessile serrated polyp (SSA/P)), suboptimal colon preparation, differences in gender, and endoscopic techniques are some of the contributing factors accounting for this difference. In this review, we will summarize the most current literature and guidelines on CRC screening and surveillance. In addition, we will describe the recent advances in endoscopic CRC screening with emphasis on colonoscopy and flexible sigmoidoscopy and the changes they have brought to the CRC landscape in the US.

Original languageEnglish (US)
Pages (from-to)284-292
Number of pages9
JournalCurrent Colorectal Cancer Reports
Issue number4
StatePublished - Aug 1 2017
Externally publishedYes


  • Colonoscopy
  • Colorectal cancer (CRC)
  • Colorectal cancer screening
  • Colorectal cancer surveillance
  • Flexible sigmoidoscopy
  • Sessile serrated polyp (SSA/P)

ASJC Scopus subject areas

  • Hepatology
  • Oncology
  • Gastroenterology


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