Combination of optoacoustics and ultrasound imaging for noninvasive, rapid assessment and management of circulatory shock

Yuriy Petrov, Irene Y. Petrov, Rinat Esenaliev, Michael Kinsky, Donald Prough

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Citations (Scopus)

Abstract

We developed a noninvasive, optoacoustic diagnostic platform for monitoring of multiple physiologic variables in inpatients and outpatients. One of the most important applications of this platform is noninvasive, rapid assessment and management of circulatory shock, a common condition in critically ill patients. At present, monitoring of circulatory shock requires measurement of central venous blood oxygenation using invasive procedures such as insertion of catheters in central veins. Hemoglobin saturation below 70% in central veins indicates circulatory shock that requires immediate treatment. We built a portable optoacoustic system for noninvasive measurement of central venous oxygenation. In this study we used the optoacoustic system and clinical ultrasound imaging systems for rapid optoacoustic probing of these veins. The optoacoustic system utilizes a custom-made, sensitive optoacoustic probe that was developed in our laboratory for monitoring of blood oxygenation in deep blood vessels. The studies were performed in human subjects with different geometry (depth, size) of the veins. The ultrasound imaging systems permitted rapid identification of specific blood vessels for optoacoustic probing. We developed a novel algorithm for continuous, real-time, and precise measurement of blood oxygenation in blood vessels. Precision of central venous oxygenation measurement obtained in the study was very high: 1%. Our results indicate that the combination of optoacoustics and ultrasound imaging systems can provide more rapid and accurate assessment and management of the circulatory shock.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7899
DOIs
StatePublished - 2011
EventPhotons Plus Ultrasound: Imaging and Sensing 2011 - San Francisco, CA, United States
Duration: Jan 23 2011Jan 25 2011

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2011
CountryUnited States
CitySan Francisco, CA
Period1/23/111/25/11

Fingerprint

Photoacoustic effect
oxygenation
Veins
Shock
Ultrasonography
veins
Ultrasonics
shock
Oxygenation
blood vessels
Blood Vessels
Imaging techniques
blood
Blood vessels
Imaging systems
platforms
Blood
Physiologic Monitoring
Critical Illness
hemoglobin

Keywords

  • Central venous oxygenation
  • Circulatory shock
  • Noninvasive monitoring
  • Optoacoustics
  • Ultrasound imaging

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Combination of optoacoustics and ultrasound imaging for noninvasive, rapid assessment and management of circulatory shock. / Petrov, Yuriy; Petrov, Irene Y.; Esenaliev, Rinat; Kinsky, Michael; Prough, Donald.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7899 2011. 78990C.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Petrov, Y, Petrov, IY, Esenaliev, R, Kinsky, M & Prough, D 2011, Combination of optoacoustics and ultrasound imaging for noninvasive, rapid assessment and management of circulatory shock. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 7899, 78990C, Photons Plus Ultrasound: Imaging and Sensing 2011, San Francisco, CA, United States, 1/23/11. https://doi.org/10.1117/12.879468
Petrov, Yuriy ; Petrov, Irene Y. ; Esenaliev, Rinat ; Kinsky, Michael ; Prough, Donald. / Combination of optoacoustics and ultrasound imaging for noninvasive, rapid assessment and management of circulatory shock. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 7899 2011.
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