Combined simultaneous endoscopic transsphenoidal and endoscopic transventricular resection of a giant pituitary macroadenoma

J. P. Greenfield, L. Z. Leng, Umar Chaudhry, S. Brown, V. K. Anand, M. M. Souweidane, T. H. Schwartz

Research output: Contribution to journalArticle

35 Scopus citations


Intrasellar and sellar-suprasellar adenomas are generally removed through a transsphenoidal approach. Giant adenomas with significant suprasellar extension often require a craniotomy or combined "above and below" approach. The use of endoscopes has increased the visualization capacity of the transsphenoidal route and made these surgeries less invasive. In this report, we describe a novel combination of the endoscopic transsphenoidal approach with the endoscopic transventricular approach to remove a giant pituitary macroadenoma extending into the third and lateral ventricles. The tumor was initially removed via an endoscopic transnasal transsphenoidal, transtuberculum, transplanum approach. A second endoscope was then advanced into the lateral ventricle through a pre-coronal burr hole to assist in mobilizing the tumor and assure a complete resection. Multi-layer closure and a ventriculo-peritoneal shunt were performed to insure a watertight seal of the skull base. Giant pituitary adenomas have traditionally been removed with staged or combined transsphenoidal and transcranial approaches. We describe the successful implementation of a minimal access endoscopic combined extended transsphenoidal and transventricular approach that avoids craniotomy and brain retraction.

Original languageEnglish (US)
Pages (from-to)306-309
Number of pages4
JournalMinimally Invasive Neurosurgery
Issue number5
StatePublished - Oct 1 2008
Externally publishedYes



  • Endoscopic
  • Giant pituitary macro-adenoma
  • Transsphenoidal
  • Transventricular

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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