Common principles in protein folding and antigen presentation

Shan Lu, Victor Reyes, Rochelle R. Torgerson, Robert A. Lew, Robert E. Humphreys

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The regular recurrence of hydrophobic amino acid residues along a peptide sequence determines the formation of a longitudinal hydrophobic strip when the peptide forms an α-helix. An understanding of the ways this may effect both folding of nascent proteins and antigen presentation should facilitate vaccine and therapeutics design.

Original languageEnglish (US)
Pages (from-to)238-242
Number of pages5
JournalTrends in Biotechnology
Volume9
Issue number1
DOIs
StatePublished - 1991
Externally publishedYes

Fingerprint

Protein folding
Protein Folding
Antigen Presentation
Antigens
Peptides
Vaccines
Amino acids
Proteins
Amino Acids
Recurrence
Therapeutics

ASJC Scopus subject areas

  • Bioengineering

Cite this

Common principles in protein folding and antigen presentation. / Lu, Shan; Reyes, Victor; Torgerson, Rochelle R.; Lew, Robert A.; Humphreys, Robert E.

In: Trends in Biotechnology, Vol. 9, No. 1, 1991, p. 238-242.

Research output: Contribution to journalArticle

Lu, Shan ; Reyes, Victor ; Torgerson, Rochelle R. ; Lew, Robert A. ; Humphreys, Robert E. / Common principles in protein folding and antigen presentation. In: Trends in Biotechnology. 1991 ; Vol. 9, No. 1. pp. 238-242.
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