Common principles in protein folding and antigen presentation

Shan Lu, Victor E. Reyes, Rochelle R. Torgerson, Robert A. Lew, Robert E. Humphreys

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The regular recurrence of hydrophobic amino acid residues along a peptide sequence determines the formation of a longitudinal hydrophobic strip when the peptide forms an α-helix. An understanding of the ways this may effect both folding of nascent proteins and antigen presentation should facilitate vaccine and therapeutics design.

Original languageEnglish (US)
Pages (from-to)238-242
Number of pages5
JournalTrends in Biotechnology
Volume9
Issue number1
DOIs
StatePublished - Jan 1991
Externally publishedYes

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ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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