The epidemiology of Clostridium difficile infection (CDI) is changing. CDI, usually depicted as a nosocomial infection in the elderly, is now occurring in community-dwelling persons who are younger and otherwise dissimilar. A more virulent isolate, North American Pulsed Field type 1, associated with increased morbidity and mortality, has been identified. In 2005, similar strains were associated with severe disease in community-dwelling patients at a rate of 7.6/100,000. Screening patients with potential CDI symptoms and implementing preventive measures, including judicious use of antibiotics, can reduce disease burden.
- Clostridium difficile infection
- Community-acquired Clostridium difficile
- North American pulsed-field type 1
- PCR ribotype 027
ASJC Scopus subject areas
- Advanced and Specialized Nursing